Manufacturing Execution System (MES) Engineer

Job Description

Join our Digital Manufacturing Team and help power the technology behind life‑saving medicines. Work in a collaborative, inclusive environment where digital innovation, manufacturing excellence and continuous learning come together to make a real impact, locally and globally as a:

Manufacturing Execution System (MES) Engineer

Welcome to our team

The Digital Manufacturing Team partners with colleagues across the business to help serve our patients and customers around the world. We are a high-energy team of dynamic, innovative individuals dedicated to advancing contribution to global medical innovation by leveraging information and technology to efficiently advance the business by driving revenue and productivity.

Purpose of the role

The Manufacturing Execution System (MES) Engineer contributes to the digital foundation that supports manufacturing operations at the Boxmeer site. The role focuses on enabling accurate, reliable, and compliant digital batch records through the effective use and evolution of the Manufacturing Execution System (MES).

This position is ideal for professionals who are developing their expertise in manufacturing systems and enjoy learning through hands on experience, collaboration, and mentoring. The MES Engineer works within a multidisciplinary environment, gaining exposure to regulated manufacturing processes, digital systems, and global ways of working, while building technical and problem-solving skills.

By supporting system reliability, participating in improvement initiatives, and engaging with the wider MES community, the role helps strengthen both local manufacturing performance and global digital capabilities.

Tasks and responsibilities include, but are not limited to

• Support daily manufacturing operations through the use and administration of Körber/Werum PAS|X.
• Assist with diagnosing and resolving MES and automation issues, contributing to investigations and corrective actions as needed.
• Configure, maintain and enhance MES recipes, workflows, and system functionality.
• Work closely with engineering, automation, IT and quality colleagues to ensure MES solutions are practical, reliable and fit for purpose.
• Support the planning, implementation and documentation of system updates and changes in line with quality standards and SDLC requirements.
• Carry out MES system administration and routine maintenance activities to help maintain validated automation environments.
• Share knowledge and learn from others by contributing to cross functional initiatives and participating in global MES collaboration forums.
• Identify improvement opportunities and contribute ideas that enhance system performance, usability and manufacturing efficiency.

Your profile

• A Bachelor’s degree in Engineering, Science or a related field.
• 2–3 years of relevant experience (including internships, graduate roles, or project‑based work) contributing to technical solutions in a collaborative environment. Experience may include manufacturing systems, automation, IT applications, data analysis, validation or quality‑driven settings.
• Ability to manage multiple priorities, communicate effectively with diverse stakeholders, and seek guidance or escalate issues when needed.
• Strong problem‑solving and troubleshooting skills, with an interest in learning and developing within an MES and regulated manufacturing environment.

What we offer

We welcome you to a truly global, dynamic and challenging environment with great opportunities for personal development. Our benefits are very competitive, and the summary below will give you an idea of what you can expect.

• Competitive salary and a 3% year-end allowance;
• 35,5 days of leave;
• Attractive collective health care insurance package with considerable reduction rates;
• Solid Pension Plan;
• Annual bonus based on own and company performance;
• Travel allowance for commuting;
• A high‑quality company restaurant offering fresh and healthy options every day.
• Excellent accessibility: the train station is located directly next to our main entrance, and there is ample parking available.
• A contribution toward your personal sports membership to support your vitality.
• A beautiful private park on site - perfect for a walk, a break or a moment of relaxation.
• Mental well‑being support through Lyra Health for you and your family members.
• Access to a dedicated prayer/meditation room.
• Extensive growth opportunities thanks to the size of the site and the wide range of disciplines and global departments represented in Boxmeer.

For questions about this vacancy

Please send an email including the vacancy number and job title to the following email address: RecruitmentNL@MSD.com.

 

So, if you are ready to:

Invent solutions to meet unmet healthcare needs, Impact the future by driving one of the world’s leading healthcare companies, and inspire your team to reach their full potential and push the boundaries of science and technology, please apply today.

Required Skills:

Digital Records Management, Driving Continuous Improvement, Manufacturing Execution Systems (MES), Project Management System, SAP MES, Software Development Life Cycle (SDLC), Werum's PAS-X MES

Preferred Skills:

cGMP Compliance, GMP Documentation, Process Improvements

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Hybrid

Shift:

Valid Driving License:

Hazardous Material(s):

Job Posting End Date:

04/9/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.