Senior Scientist. Stromal Immunology

Job Description

We are seeking a highly motivated Senior Scientist in Stromal Immunology to be fully lab based at our Company's Cambridge location.  

Join our Immunology team in Cambridge, Massachusetts, and help shape the future of treatments for inflammatory and autoimmune diseases. In this role you will evaluate and apply novel experimental approaches, partnering across departments with discovery teams to implement cutting-edge laboratory technologies. You will drive the identification of innovative therapeutic targets and contribute directly to the development of new therapies and medicines that improve patient lives. This is an opportunity to work at the forefront of immunology research, translating scientific advances into meaningful clinical impact.

We are seeking an enthusiastic scientist with a strong track record of delivering timely, robust data packages. The ideal candidate will be able to work independently, able to design and execute their own experiments, and comfortable taking projects from conception through to clear, reproducible results. You should be proactive in problem-solving, able to communicate findings effectively to multidisciplinary teams, and committed to advancing research that leads to novel therapies and improved patient outcomes.

What you will do: 

• Design and execute experiments, analyze and interpret complex dataset to identify and validate novel targets in immunology/ inflammation/autoimmunity 

• Apply knowledge of key signal transduction pathways to design appropriate experiments 

• Be a key contributor in lab and in meetings to progress multiple programs 

• Conceptualize and enact innovative approaches (including novel technologies) to solve program objectives and issues 

• Manage project-specific milestones and timelines 

• Communicate science and strategy to stakeholders and management 

• Collaborate effectively both internally & externally, within and across functional areas  

• Demonstrates a “one-team” mindset by proactively engaging in and leadership of lab and department initiatives 

• Actively participates in cultural initiatives & embraces DE&I principles, promotes psychological safety and supports a work environment that positively influences others and enables all to bring their true selves to work 

What you will need to be successful in this role: 

Required Experience:  

• B.Sc in Biological Sciences, Immunology, Pathology, Biochemistry, Biotechnology, Biomedical Engineering,  ore related STEM field with  7+ years of professional research experience,  M.Sc. with 4+ years of professional research experience or PhD and 0+ years of experience.

• Deep knowledge of inflammatory and autoimmune disease mechanisms

• Hands on experience in assay development, optimization, qualification/validation, and troubleshooting across multiple cellular immunology techniques such as flow cytometry (including multicolor panel design and analysis), proliferation, cytotoxicity assays.

• Practical experience in designing and executing complex multicellular systems and co-culture models.

• Strong ability to interpret data from biological, biochemical, and immunological assays and to design appropriate follow-up experiments.

• Familiarity with immunofluorescence microscopy/ high-content imaging is preferred

Skills/Competencies 

• Strong problem-solving and critical thinking abilities

• Intellectual curiosity and proactive approach to staying current with the field

• Attention to detail and high standards for data quality and reproducibility

• Adaptability and resilience in a fast-paced research environment

• Team player with effective written and oral communication skills 

• Good organizational and time management skills 

#EligibleforERP

Required Skills:

3D Cell Culture, Autoimmune Diseases, Cell Culture Techniques, Cytotoxicity Assays, Fibroblasts, Fibrosis, Flow Cytometry, Immunology, Inflammatory Diseases, Multi-Color Flow Cytometry, Primary Cell Culture, Tissue Cell Culture

Preferred Skills:

High Content Imaging

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$119,100.00 - $187,500.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

OEB4, BSL2

Job Posting End Date:

05/4/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.