Thermo Fisher

qPCR Molecular Biologist, Scientist II

Singapore, Singapore Full time

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Cold Room/Freezers -22degreesF/-6degrees C, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

Key Responsibilities 

  • Design, develop, and optimize qPCR assays for gene expression, genotyping, copy number variation, and pathogen detection. 

  • Plan and execute experiments independently, ensuring data quality, reproducibility, and technical excellence. 

  • Perform nucleic acid extraction, cDNA synthesis, and quantification using standard molecular methods. 

  • Validate assay performance (sensitivity, specificity, and efficiency) and analyze results using platforms such as Applied Biosystems QuantStudio™ or Bio-Rad CFX Manager. 

  • Troubleshoot technical issues and implement improvements to enhance assay performance. 

  • Maintain detailed experimental records and prepare technical reports, SOPs, and validation documentation. 

  • Collaborate with product development, bioinformatics, and assay design teams to integrate molecular workflows. 

  • Ensure adherence to safety protocols, quality systems, and regulatory requirements (ISO, GLP, CLIA). 

 

Qualifications 

Education: Bachelor’s or Master’s in Molecular Biology, Biochemistry, Genetics, or a related life sciences discipline. Experience requirements will vary based on degree. 

Experience: 

  • Minimum of 1-4 years of hands-on experience performing qPCR . Experience requirements will vary based on degree. 

  • Prior experience with assay development, validation, and data analysis. 

  • Familiarity with nucleic acid extraction instruments is a plus. 

Technical Skills: 

  • Understanding of molecular biology principles, qPCR kinetics, and assay troubleshooting. 

  • Strong analytical and problem-solving skills with a data-driven mindset. 

  • Strong understanding of qPCR principles, primer/probe design, and amplification kinetics. 

  • Proficiency in data analysis, statistical interpretation, and report generation. 

  • Experience working under quality and regulatory standards preferred. 

Soft Skills: 

  • Excellent organizational, communication, and problem-solving skills. 

  • Ability to work independently as well as collaboratively in a multidisciplinary environment. 

  • Strong attention to detail and scientific curiosity. 

 

Preferred Qualifications 

  • Familiarity with bioinformatics tools for assay design 

  • Experience with NGS 

  • Experience with digital PCR (dPCR) 

  • Experience with qPCR multiplexing 

  • Knowledge of automation and data management systems.