Pfizer

Principal Scientist - Process Analytical Technology

United States - Michigan - Kalamazoo Full time

Use Your Power for Purpose

Work effectively in a fast-paced, customer-oriented, laboratory/production environment to implement process analytical technology (PAT) that supports Active Pharmaceutical Ingredient (API) and Drug Product (DP) Manufacturing Operations.  Identify, develop, and deliver PAT applications in support of commercial manufacturing in Kalamazoo.  Support the Process Analytical Technology (PAT) program and the Operational Excellence initiatives utilizing advanced analytical, chemometric, and data science skills to upgrade process performance and/or increase process knowledge. Support product transfers, new product development, and cost improvement projects. 

ROLE RESPONSIBILITIES

  • Implement technical solutions and analytical strategies using PAT.

  • Lead adoption and use of PAT instruments and machine learning models.

  • Assess feasibility and ensure technical soundness of instruments/models for process monitoring and control.

  • Apply scientific concepts across chemistry, PAT, and data science with high learning agility.

  • Support automation development between PAT tools and process data systems (e.g., AVEVA Pi).

  • Mentor and develop scientific staff; promote growth and knowledge sharing.

  • Plan and manage short- and long-term development activities, timelines, and resource allocation.

  • Foster diverse perspectives to drive innovative solutions.

  • Coordinate instrumentation usage across projects for equitable access.

  • Contribute to technical documentation (SOPs, tech transfer, process diagrams, regulatory submissions).

  • Ensure compliance with development quality, regulatory, HSE, GLP, and GMP requirements.

Here Is What You Need (Minimum Requirements)

  • Applicant must have a bachelor's degree with at least 4 years of experience; OR a master's degree with at least 2 years of experience; OR a PhD with 0+ years of experience; OR as associate's degree with 8 years of experience; OR a high school diploma (or equivalent) and 10 years ofrelevant experience.


Bonus Points If You Have (Preferred Requirements)

  • Minimum 3 years with production applicable PAT experience is preferred. 

  • Broad spectroscopy background preferred with the ability to perform multi-variate data analysis. 

  • Demonstrated ability to program in R, Python, and/or MATLAB is preferred.

PHYSICAL/MENTAL REQUIREMENTS

The position involves working in a laboratory/production environment, which may include standing for long periods of time and working with chemicals. The position requires the ability to perform mathematical calculations including complex data analysis. 

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

The position may require colleagues to work off-hours, weekends and/or holidays to meet business or customer needs.

Relocation support available **

Work Location Assignment: On Premise

The annual base salary for this position ranges from $96,300.00 to $160,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

Research and Development