Principal Scientist - Molecular Genomics

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Able to lift 40 lbs. without assistance, Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Cold Room/Freezers -22degreesF/-6degrees C, Fluctuating Temps hot/cold, Laboratory Setting, Loud Noises (Equipment/Machinery), Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.), Will work with hazardous/toxic materials

Job Description

Position: Principal Scientist

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Our PPD® Laboratory Services team has a direct impact on improving patient health through the expertise of scientists, industry thought-leaders and therapeutic experts. As the world leader in serving science, our laboratory professionals bring their dedication to accuracy and quality to deliver groundbreaking innovations.

A day in the Life:

• Oversee setup, qualification, and validation of an NGS instrument (e.g. Illumina, PacBio, Ultima)
• Lead evaluation and implementation of spatial sequencing technologies (10x Genomics Chromium, Visium, Xenium)
• Develop and implement the sequencing strategy for the lab, in line with organizational and client objectives
• Mentor scientists and analysts in NGS workflows, QC, and data interpretation
• Partner with automation, bioinformatics, and proteomics teams for multi-omics integration
• Represent the lab in vendor partnerships, conferences, and technical collaborations

Education

• Bachelor's degree in lab sciences such as biology, biochemistry, immunology, chemistry, molecular biology or equivalent and relevant formal academic / vocational qualification. Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 12+ years).
• Master's degree in lab sciences such as biology, biochemistry, immunology, chemistry, molecular biology or equivalent and relevant formal academic / vocational qualification. Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 10+ years).
• PhD degree in lab sciences such as biology, biochemistry, immunology, chemistry, molecular biology or equivalent and relevant formal academic / vocational qualification. Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 8+ years).
• In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills, Abilities

• Expert knowledge of sequencing chemistry, data QC, and assay validation

• Experience integrating sequencing with proteomics or other omics technologies ​

• Strong communication and external collaboration skills
• Strategic approach with ability to identify and implement new technologies
• Demonstrated success mentoring staff and building scientific teams
• Coding experience (e.g. R, Python, C#). R coding experience is preferred
• Communicate clearly and follow detailed written and verbal instruction
• Fully independent ability of time management to complete assignments in required time frame
• Able to maintain an organized working environment

Work Environment

Thermo Fisher Scientific values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
• Able to work upright and stationary and/or standing for typical working hours.
• Able to lift and move objects up to 25 pounds.
• Able to work in non-traditional work environments.
• Able to use and learn standard office equipment and technology with proficiency.
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.