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As a student internship at Catalysis & Flow Reactions (C&FR) you will be working in the department “Process Chemistry & Catalysis” within the unit “Synthetic Molecules Technical Development” (PTDC-C). Behind every product sold by Roche is the strong involvement of Pharma Global Technical Operations (PT). Starting with Phase 1 of the clinical development process and continuing through to product maturity, PT makes medicines at sites around the world and includes more than 10.000 employees worldwide. In Synthetic Molecules Technical Development (PTDC) as part of the Global Technical Development (PTD) unit we bring a broad range of experience across drug substance (DS), drug product (DP), analytical sciences and manufacturing technology. We collaborate closely with key partners in the departments Research and Early Development (pRED/gRED), commercial manufacturing (PTC) and PTD and we are responsible for late stage technical development of our small molecule pipeline, manufacture of DS and DP for clinical studies and transfer of the processes to commercial manufacturing.
Development of metal-catalyzed reactions for general application and internal Roche projects.
Synthesis and characterization of new ligands and metal catalysts under strict exclusion of air.
Benchmarking newly prepared catalysts in standard reactions like cross-couplings and asymmetric hydrogenations.
Integration of catalysts into ongoing Roche process steps and project workflows.
Operation of metal-catalyzed reactions under pressure using autoclaves.
Safe handling of gases such as $H_{2}$ and $CO$ in high-pressure environments.
Utilization of state-of-the-art laboratory equipment including parallel screening reactors and glove boxes.
You are an enrolled student in a Master program or hold a master with a focus on organic, inorganic or metalorganic chemistry.
A solid background in synthetic organic and organometallic chemistry.
Experience in synthesis of ligands and/or metal complexes under inert atmosphere and their application in metal-catalyzed reactions.
Experience with high pressure set-up.
A strong interest in scientific and technical innovation.
An excellent team player and have very good coordination and communication skills with proficiency in English and German.
A pro-active knowledge sharer with excellent organizational skills.
Additional experience in the field of non-noble metal catalysis is an advantage.
Please upload both your CV and a cover letter with your application.
Non-EU/EFTA citizens (m/f/d) must attach a confirmation from the university to the application documents stating that a mandatory internship is part of the training.
Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity!
A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let’s build a healthier future, together.
Roche is an Equal Opportunity Employer.