In Vivo Biologist- Immunology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organizational Overview:   Lilly Immunology Discovery is dedicated to identifying novel therapeutics to treat the myriad of autoimmune diseases impacting patients around the globe.  We are currently seeking a motivated biologist to work as an integral part of our immunology in vivo pharmacology group.  The main responsibility of this group is to develop and validate disease models of inflammation and autoimmunity for the interrogation of novel therapeutics within Lilly Immunology Discovery.  Located at the Lilly Biotechnology Center in San Diego, our pharmacology group supports projects directed both in San Diego, Boston, and the Corporate Center in Indianapolis.

Responsibilities:  This position requires prior experience in the development of small animal models of inflammation and conducting in vivo efficacy studies according to study protocols.  The candidate will be responsible for all aspects of the in-life portions of studies and be involved in post study sample processing and data analysis.  In addition, the position will perform in vitro assays of study tissue samples. The applicant should desire to work in a team environment as the position must work in unity with other members of the pharmacology group and interact with various immunology members and cross-functional colleagues.

• Perform all aspects of in vivo experiments: dose formulation, animal handling, dosing (PO, IP, SC, ID, IV), blood collection, small animal surgery, and tissue collection/processing and the planning thereof within the pharmacology team.
• Analyze and graph data for review.
• Perform ELISAs (or similar platform) on study samples.
• Organize data and present findings at team meetings.

Requirements:

• BS or MS in physiology, biology, pharmacology or closely related field with 2+ years of in vivo experience.

Additional Skills/Preferences

• Skilled in dose formulation, animal handling, blood collection, animal surgery, and tissue collection/processing.
• Experienced using Excel and GraphPad Prism for analysis and statistics
• Diligent record keeping
• Ability to design, analyze, and interpret study results
• Good organizational and communication skills.  The position will be required to present results in internal meetings.
• Knowledge of molecular biology (e.g. RNA isolation, RT-PCR).
• Familiarity with imaging processes (IHC/IF, IVIS, Phenocycler), FACS analysis and FloJo, and/or cell culture techniques a plus.

Additional Information: This position will require occasional weekend work

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Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$71,250 - $187,000

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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