Be part of fulfilling our ambition to be world leaders in Oncology. We are already the fastest growing team within AstraZeneca and across the industry, and there are countless new indications and targets in our game-changing pipeline. We deliver this value through launch excellence, commercial effectiveness and maximizing the lifecycle. By leveraging our commercialized portfolio, we are confident we can change the practice of medicine and redefine cancer treatment.
We have an exciting opportunity within the Global Hematology Franchise as Global Marketing Director, Calquence. Within the Global Calquence team, this role plays a critical part in shaping the future of the brand by leading the DLBCL strategy and driving a robust lifecycle management (LCM) and loss of exclusivity (LOE) strategy.
Reporting to the Global Commercial Head, this role is responsible for defining and delivering the global strategy for DLBCL, including preparation for key data readouts such as ESCALADE, while ensuring strong alignment with markets and cross-functional teams. In parallel, the role leads the development of a comprehensive LCM and LOE strategy, including scenario planning, value optimization, and long-term brand sustainability.
This position works in close collaboration with global, regional, and market stakeholders across the US, Europe, and International regions, as well as with key headquarters functions including Marketing, Global Analytics & Insights (GA&I), Digital, Pricing and Market Access, Global Medical Affairs (GMA), Regulatory Affairs, R&D, and Product Development.
Key responsibilities
Lead DLBCL Strategy and ESCALADE Preparation
Lead global DLBCL commercial strategy development
Maintain leadership of the ESCALADE program preparation, supporting readiness for the expected HLR in 2027
Collaborate with cross-functional partners to ensure strong preparation for potential future launches
Insights & Strategic Opportunity Identification
Partner with Global Analytics & Insights to generate deep understanding of the evolving treatment landscape
Engage with key external experts and stakeholders to inform strategy
Translate insights into clear strategic opportunities and business cases
Cross-Functional Leadership
Collaborate with global and regional stakeholders across Marketing, Medical, Market Access, Regulatory and R&D
Drive alignment across complex cross-functional initiatives
Contribute to building AstraZeneca’s leadership in hematology
LOE Strategy & Preparedness
Lead LOE planning and readiness
Develop and maintain robust scenario planning (timelines, risks, opportunities)
Define mitigation strategies to protect and maximize value post-LOE
Collaborate with Legal/CI on: Patent landscape monitoring, LOE timing assumptions, Risk/opportunity assessment
Integrate competitive dynamics into lifecycle planning
Work closely with regions and markets to translate LCM strategy into actionable execution plans, identify local levers to maximize value, and ensure readiness for LOE transition scenarios
Strategic Planning & Governance
Support senior leadership discussions with clear, data-driven insights
Ensure consistency across indications and lifecycle phases
Requirements
Bachelor’s degree in a relevant Science subject
3+ years Experience in Oncology marketing
Broad global commercial experience including pre-launch and launch
Proven experience and knowledge of a broad base of external customers including patients, prescribers, payers, and providers
Demonstrated use of insights to deliver effective strategy
Evidence of developing compelling business cases
Ability to simultaneously manage multiple priorities with a high degree of autonomy
Desirable attributes:
Experience in Hematology
Strong clinical acumen and scientific mind-set
Business Insights experience
Global launch experience preferred
Date Posted
06-May-2026Closing Date
20-May-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.