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As the Downstream Engineer II, you will assist in design and execution of experiments aimed at improving robustness, capacity, and productivity of commercial downstream processes in the Manufacturing Sciences – Commercial Manufacturing Support Laboratory group.
Assist in design and execution of experiments aimed at improving robustness, capacity, and productivity of commercial downstream processes
Provide experimental support and technical expertise for troubleshooting of process discrepancies
Maintain lab equipment; identify and implement improvements in lab operations
Write and review study proposals and development reports
Maintain process description documents and participate in product trend reviews
Strong interest in learning and developing proficiency with data analytics and visualization tools such as JMP, SIMCA, and Power BI etc.
MS in Chemical Engineering or related disciplines; or BS in Chemical Engineering or related disciplines with a minimum of 1 year of experience.
Hands-on experience in lab scale protein purification preferred
Experience with tech transfer and/or GMP manufacturing support preferred
Has basic knowledge of protein purification unit operations
Has basic understanding of data analysis and statistically driven experimental design (DoE).
Be able to influence, motivate, and drive technical rigor when participating on cross-functional teams.
Demonstrate teamwork/collaboration and the ability to communicate appropriately and effectively.
Have the attitude to proactively learn new technologies
Under supervision, plan and execute experimental studies
Assist in analyzing complex technical problems, then finding and implementing solutions.
Provide input to departmental management towards making functional decisions.
Work closely with his/her supervisor and coworkers in managing multiple work streams and projects.
Internally, this individual will represent the group to support manufacturing as a customer, with close interactions with the internal business partners including PD, QA, RA and ENG within Takeda.
Externally, this individual will interact with vendors who may supply materials or equipment both used in the small-scale development lab and in large- scale manufacturing.
At Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role, you may:
Work in a controlled environment requiring special gowning and wear protective clothing over the head, face, hands, feet and body. This may include additional hearing protection for loud areas.
Need to remove all make-up, jewelry, contact lenses, nail polish and/or artificial fingernails while in the manufacturing environment.
Work in a cold, wet environment.
Work multiple shifts, including weekends, or be asked to work supplemental hours, as necessary.
Work around chemicals such as alcohol, acids, buffers and Celite that may require respiratory protection.
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
#GMSGQ #ZR1 #LI-Onsite
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - MA - Lexington - BIO OPSU.S. Base Salary Range:
$71,800.00 - $112,860.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Job Exempt
YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.