Pfizer

Director, Global Sigvotatug Vedotin

United States - New York - New York City Full time

ROLE SUMMARY

At Pfizer Oncology, we are committed to “Outdo Cancer” by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today, Pfizer Oncology has an industry-leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast, genitourinary, hematology-oncology and thoracic therapeutic areas.  Thoracic represents a crucial component to achieve Pfizer’s overarching strategic ambition in Oncology; thoracic is estimated to represent ~25% of Pfizer Oncology’s 2030 global sales.  Collectively, our focus is on building upon our foundation in lung precision medicine to accelerate new standards of care in broader populations. 

Despite therapeutic advances in lung cancer, there remains significant unmet patient need.  Each year, there are ~2.7 million new lung cancer cases globally.  The lung cancer therapies market is expected to grow from $45B in 2025 to $70B in 2030 globally. 

Core to Pfizer’s lung cancer strategy is realizing the potential of our first-in-class antibody drug conjugates (ADCs), namely our potential first-in-class integrin-Beta-6 (IB6)-targeting ADC, sigvotatug vedotin (SV).  >90% of NSCLC tumors express integrin Beta-6.  The first commercial launch of SV in lung cancer, specifically 2L+ NSCLC, is being planned for 1H 2027; followed by 1L NSCLC PD-L1 TPS >50% in 2H 2028.  SV is also being studied in 1L NSCLC (any PD-L1 TPS).

In Global Marketing, we translate science into value for patients.  Our remit is to own the strategic direction across the asset lifecycle, ensure long-term value creation and preservation, and drive brand consistency across markets and efficiencies in execution.

This role will report to the Global Commercial Lead for SV. 

ROLE RESPONSIBILITIES

  • Partner with US and International commercial colleagues, Global Medical Affairs, Global Access & Value, PGS and Regulatory to ensure global launch readiness for SV
  • Lead delivery of Global Integrated Launch Strategy (ILS)
  • Establish launch sequence with markets and Regulatory and ensure GPT endorsement of key changes to launch sequence
  • Coordinate with US/ICO/select markets to track launch performance and launch readiness in DLPP and escalate key issues
  • Drive OGSM KPI development and ensure launch metrics are thoughtfully developed and aligned with US and International; update key leadership dashboards (e.g., Launch Health Report)
  • Execute cross-functional and Global/US/ICO launch readiness meeting(s)
  • Partner with Thought Leader Strategy Lead and Global Medical Affairs to develop Global SV KOL Engagement Strategy
  • Collaborate effectively with R&D, Regulatory, Global Access & Value, Global Medical Affairs, Customer Analytics & Insights, Finance, PGS, US, and International. 
  • Conduct all activities and make decisions that are in accordance with Company policies and SOPs, Pfizer Values & global regulatory guidelines, and requests consultation when navigating uncertain situations.

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  • Bachelor’s degree and 8+ years of commercial experience in the pharmaceutical industry
  • Marketing experience
  • Strong strategic thinking, analytical skills, detail and action oriented, creative, flexible, self-motivated
  • Ability to work independently and demonstrates judgement of what needs to be escalated
  • Strong team player with demonstrated ability to engage experts from a wide range of functional areas to improve business performance and find a path forward
  • Excellent verbal and written communication skills for a wide range of audiences
  • Is a role model for the Pfizer Values

PREFERRED QUALIFICATIONS

  • Advanced degree
  • Global or US Marketing experience is required

  

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Ability to travel approximately 20% of the time

Other Job Details:

Last Date to Apply for Job: November 24th, 2025

Additional Location Information: New York, NY; Collegeville, PA; Cambridge, MA; Bothell, WA, Europe - Any Pfizer Site

Eligible for Relocation Package: No

#LI-PFE

The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

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