General Medicines is a £10 billion business (30% of GSK sales) and is expected to maintain stable turnover over the next three years. The International Markets business grew 4% in 2025 to reach £8.2 billion, making it the second-largest region after the US, and it is on track to deliver high single-digit profitable growth in General Medicines in 2026. In this context, GSK’s Primary & Small Molecules (PSM) network manufactures most of General Medicines’ volumes, supporting circa 60% of revenues and more than 30% of the growth.
The VP, Local to Local Operations role is instrumental in delivering this commercial ambition, with overall accountability for executing company strategy and delivering P&L across 8 of the 14 manufacturing sites in the Primary & Small Molecules network, operating across North Africa, the Middle East and Asia (Algeria, Egypt, Japan, Saudi Arabia, and Pakistan). The role is accountable for ensuring performance excellence across the GSK portfolio in the area, as well as for the strategic direction established in collaboration with the Local Operating Companies (LOCs).
Drive and manage the business
• Together with the SVP, Primary & Small Molecules, and the Global Supply Chain (GSC) strategy group, define the Local to Local manufacturing operations strategy, ensuring the highest level of delivery, commercial alignment, and returns.
• Together with the Local to Local Leadership Team, deliver the objectives of the business in partnership with Commercial, driving one P&L mindset and business impact.
• Together with the Site Directors, partner with Commercial to maximise gross margin through appropriate cost, profit, and revenue goals.
• Drive operational performance and ensure continuous supply of medicines in the markets, in line with GSK KPIs and meeting customer needs.
• Manage GSK resources effectively to deliver the longer-term strategy, portfolio evolution, and performance ambition.
• Provide leadership to Site Directors and manufacturing sites to ensure a continuous supply of medicines. Ensure flawless operational delivery across sites, at the right cost and with the right quality.
• Ensure the Site Directors lead with an enterprise mindset, building market agility and ensuring commercial alignment.
• Effectively manage GSK Enterprise Risks and Compliance and be relentlessly focused on Safety.
• Be accountable for ensuring GSK operates in line with all locally and globally applicable laws, policies, SOPs, and legislation, including EHS, Quality, and financial reporting.
• Ensure regulatory alignment.
People
• With the Local to Local Leadership Team, provide leadership and engage all employees in delivering the objectives to expectations.
• Inspire, engage, and align employees to understand and deliver the strategy.
• Lead, evaluate, and develop senior leaders and teams, and have the ambition to foster Enterprise leaders.
• Foster a high-performing team environment, in compliance with all relevant internal and external regulations and laws.
• Attract, develop, and retain talent at all levels to ensure quality succession plans for priority roles in the organisation.
Performance culture
• Be a role model and set the right tone from the top in embedding the GSK culture.
• Drive a culture of continuous improvement and learning and personally drive LEAN and Digital as a way of working.
• Create an environment that recognises and rewards high performance and actively manages underperformance.
• Create an atmosphere of trust, fostering open and honest conversations across the organisation, and be an active communicator.
Corporate reputation & trust
• Initiate and grow appropriate relationships with external bodies, health communities, and industry associations.
• Build strong cross-functional relationships to maximise synergies and make sure that GSK has unified, coherent, and trusted representation externally.
• Embed a preventive EHS mindset within Local to Local Operations.
• Build a strong quality culture within Local to Local Operations.
• Ensure site compliance of all operations with Quality and Regulatory requirements.
• Ensure all respective sites comply with GSK and local health, safety, and environment requirements.
• Maintain good relationships and a good employee relations environment.
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:
• Proven leadership experience running an independent site in the pharmaceutical sector.
• Experience in pharmaceutical manufacturing operations and with quality, compliance, and risk requirements in a pharmaceutical environment.
• Experience in building a culture of continuous improvement and embedding strong safety and quality systems and behaviours.
• Experience in leading leaders across cultures and building high‑performing, inclusive teams.
• Fluent in English and able to travel internationally.
Preferred Criteria
• Proven leadership experience running multiple manufacturing sites or a manufacturing network in the pharmaceutical sector.
• Additional experience in regional or global Quality, Supply Chain, or Engineering roles, or leading sites in different business contexts.
• Experience working across developed and emerging markets or with multi-country operations.
• Ability to anticipate future opportunities and challenges and turn them into clear operational goals.
• Engaging, empowering, inclusive, and decisive leadership style with well-developed relation building skills to build trust and credibility and establish networks across markets, Commercial and other functions at a regional and global level.
• Enterprise thinking.
• Cultural sensitivity and ability to work effectively across cultures.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
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