Work Schedule
Standard (Mon-Fri)Environmental Conditions
Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Cleanroom: no hair products, jewelry, makeup, nail polish, perfume, exposed piercings, facial hair etc... allowed, Loud Noises (Equipment/Machinery), Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Standing for full shift, Strong Odors (chemical, lubricants, biological products etc.), Will work with hazardous/toxic materialsJob Description
At Thermo Fisher Scientific, every day is an opportunity to contribute to an essential mission: enabling our customers to make the world healthier, cleaner, and safer.
By joining our teams in Seneffe, you will thrive in a cutting-edge biopharmaceutical environment, at the heart of high-impact clinical projects, while benefiting from the resources, training, and opportunities necessary to develop your career.
About the Seneffe Site
The Seneffe site is a strategic biopharmaceutical facility specializing in USP (Upstream Processing, or cell culture) activities in a cGMP environment, dedicated to the production of clinical batches within a highly regulated framework.
Your Daily Impact
You will play a key role in the success of clinical projects by ensuring the rigorous, compliant, and traceable execution of USP activities.
Thanks to your understanding of production processes, quality requirements, and technology transfers, you will directly contribute to the delivery of reliable clinical batches that meet regulatory standards.
You will support both the R&D team and the GMP production team.
A Typical Day in the Role
• Participate in shift handovers and team briefings to review priorities, production schedules, and quality/technical constraints.
• Enter the production area after donning protective clothing according to safety and biosecurity protocols.
• Perform pre-production checks: line clearance, equipment, raw materials, and production documentation.
• Execute USP production activities in strict compliance with SOPs, batch records, and GMP requirements.
• Document all operations in real time to ensure complete traceability.
Main Responsibilities
• Execute upstream production steps according to the established schedule and under the supervision of the line manager and production manager, adhering to written instructions and current procedures.
• Comply with Standard Operating Procedures (SOPs) and Good Manufacturing Practices (GMP).
• Complete activity logs in real time, following Good Documentation Practices (GMP) when batches are produced under GMP conditions. • Report any problems encountered to the line manager, scientist, and/or manager
• File non-conformity reports and participate in investigations
• Ensure the preparation of areas, materials, equipment, and the production line
• Participate in line clearances at the beginning, middle, and end of the campaign
• Set up the necessary equipment for production
• Prepare the buffers/mediums (weighing, dissolving, measuring, pH adjustment, filtration or autoclaving, packaging, and labeling) required for production
• Receive, verify, and enter transfer requests into the building and the production area. Manage sterile components, workflows, and unpacking requirements
• Perform in-process control tests to monitor processes
• Support the preparation (cleaning/washing, packaging, and sterilization) of production equipment
• When production takes place under GMP conditions, perform microbiological and particulate testing of production areas (viable, non-viable) and ensure that results are submitted to QC within the deadlines established in the procedures.
• Ensure daily and weekly cleaning of production areas after activity, and assist with cleaning the various production buildings according to the schedule established by management and cleaning requirements.
• Monitor inventories and ensure proper traceability of items used during activities in the area.
Desired Profile
Education
• High school diploma or equivalent required
• Technical training (Aptaskil or equivalent) preferred
Experience
• Minimum 2 years of experience in production, operations, laboratory, or a similar industrial environment
• Experience in a cGMP environment is essential
• Experience in a cleanroom/classified area is an asset
Key Skills
• Rigor, attention to detail, and strict adherence to procedures
• Ability to work in a team within a regulated environment
• Good understanding of production flows and GMP documentation
• Progressive autonomy and a continuous improvement mindset
Work Environment
• Work in classified production areas
• Use of PPE and strict adherence to safety regulations
Benefits
• Medical insurance
• Attractive paid leave/annual leave
• Employee referral program
Real career advancement opportunities within an international group