Thesis Work, 60 credits - High-throughput in vitro assay development for targeting RNA with small molecules

Are you fascinated by the frontier of RNA-targeted drug discovery? Join our team to develop novel high-throughput assays and screen small molecules that modulate RNA–protein interactions. As part of a world-class research group, you will design, execute, and validate cutting-edge in vitro assays, gaining hands-on experience with advanced technologies (TR-FRET, AlphaLISA), experimental design, data analysis, and scientific communication. Contribute directly to innovative research that could reveal new pathways for therapeutic development! 

About AstraZeneca:  

AstraZeneca is a global, science-led, patient-centered biopharmaceutical company focusing on discovering, developing, and commercializing prescription medicines for some of the world’s most serious diseases. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.   

About the Opportunity:  

As a Thesis Worker at AstraZeneca, you’ll find an environment that’s full of unique opportunities and exciting challenges. Here, you’ll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. You’ll be working on meaningful projects to make an impact and deliver real value for our patients and our business. 

Thesis work description: 

In this master’s thesis, you will explore the frontiers of RNA-targeted drug discovery by investigating RNA–protein interactions and developing novel high-throughput in vitro assays. Your work will focus on designing, optimizing, and validating assays to screen small-molecule libraries for modulators of RNA–protein complexes, using advanced technologies such as TR-FRET and AlphaLISA. 

You will gain hands-on experience in the design of experiments (DoE), high-throughput assay development and validation, quantitative data analysis, and scientific thesis writing. As a member of a collaborative research team, you will carry out lab experiments, interpret your data, present findings in scientific meetings, and actively contribute to the overall progress of the project. 

Placement: 

This is an on-site position at AstraZeneca Gothenburg.  

AstraZeneca does not support accommodation for this role.  

Structure: 

Start: Fall term 2026 

Credits: 60 

Essential Requirements: 

• Enrolled in a Swedish University 
• A bachelor’s degree in life sciences with a strong focus on biochemistry and cell biology. 
• Excellent organizational skills, with the ability to work effectively across teams and functions. 
• Excellent English communication skills, including speaking, presenting and scientific writing. 
• Hands-on experience with in vitro assays. 

So, what is next?  

Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can’t wait to hear from you!  

We welcome your application as soon as possible, but ahead of the scheduled closing date April 10, 2026. In the event that  we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.  

Date Posted

20-Mar-2026

Closing Date

10-Apr-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.