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Position Summary
The Sr. Manager, Cell & Gene Therapy Financial Performance plays a critical role within US Oncology Network (USON) Finance by serving as the subject matter expert for the financial performance of Cell & Gene therapies across the network. This position is accountable for developing the financial performance framework for Cell & Gene—including definitions, measurement methodology, and executive-ready reporting—while partnering closely with practices and cross-functional stakeholders to ensure performance is understood, accurate, and actionable.
This role translates complex, evolving therapy economics into clear financial insights for executive leadership. It leads modeling and scenario analysis across key drivers (utilization, site-of-care dynamics, acquisition and reimbursement, program costs, and timing impacts), and it establishes repeatable reporting that supports decision-making, performance improvement, and strategic planning.
Operating at the intersection of finance, operations, and strategy, the Sr. Manager drives continuous improvement in data quality, analytical tools, and governance for Cell & Gene financial performance. By maintaining disciplined, transparent analytics and communicating results with executive presence, this role supports USON’s mission and enables sound financial stewardship as these therapies scale.
Key Responsibilities
Serve as the finance subject matter expert for Cell & Gene Therapy performance across USON, owning the end-to-end performance measurement approach (definitions, key metrics, methodology, and controls).
Establish standardized performance views and interpretation guidelines to ensure consistent understanding across practices and stakeholders.
Lead development and refinement of financial models that explain and forecast Cell & Gene performance, focusing on transparency, accuracy, and decision usefulness.
Practice & Stakeholder Partnership / Performance Determination
Partner directly with practices and key stakeholders (FP&A, Finance Ops, Revenue Cycle, Managed Care, operations/clinical partners as applicable) to determine and validate Cell & Gene financial performance.
Investigate performance drivers and variances, ensuring results are well-supported, reconciled, and communicated in business terms.
Translate practice-specific realities into consistent network-level reporting and comparable performance narratives.
Executive Reporting & Decision Support
Deliver concise, executive-ready reporting packages, including performance commentary, variance explanations, and forward-looking outlooks.
Present findings and recommendations with strong executive presence, tailoring content for senior leadership decision-making.
Build “so what” insight: clarify risks, opportunities, and key actions based on the financial performance signals.
Modeling, Scenario Planning & Forecasting
Develop scenario models (volume, timing, reimbursement sensitivity, program cost structures) to support budgeting/forecasting and strategic planning for Cell & Gene growth.
Create driver-based views that allow leadership to understand what is changing, why, and what levers exist.
Support annual planning cycles and in-year updates with disciplined assumptions and documented logic.
Data, Reporting Automation & Visualization
Build and enhance repeatable reporting and dashboards (Excel and/or Power BI) that provide timely, accurate Cell & Gene financial performance visibility.
Improve efficiency through automation and standardized data pipelines, while maintaining strong data governance and controls.
Ensure reporting is consistent, auditable, and easy for business partners to consume.
Strategic Initiatives, Governance & Continuous Improvement
Lead or contribute to strategic initiatives related to Cell & Gene financial performance measurement, process improvement, and analytics maturity.
Establish governance routines (documentation, metric definitions, refresh cadence, stakeholder alignment) to support scaling and sustainability.
Identify emerging needs and proactively recommend enhancements to tools, processes, and performance management.
Minimum Requirement
Education
Critical Skills
Prior FP&A experience performing budget, forecast, plan, variance analyses
Excellent financial modeling and problem-solving skills
Intermediate skills in Excel (formulas, modeling, pivot tables) and PowerPoint
Financial systems experience with ability to reconcile information from multiple sources
Additional Knowledge & Skills
Strong internal and external customer service and relationship-building skills
Executive presence and experience with presentations to various leadership levels
Ability to provide strategic recommendations and influence stakeholders to make decisions
Excellent project management skills
Intellectual curiosity & highly independent
Motivated self-starter that is well organized, dependable, efficient and results-oriented
Strong time management and organization skills with flexibility to work in a fast-paced and changing work environment
Experience collaborating with C-suite executives
Ability to collaborate with teams across multiple functions to affect a solution
Prior leadership experience a plus
This role is a hybrid position. The selected candidate is expected to work on-site at our Las Colinas office a minimum of two (2) days per week, with the remaining days worked remotely. Specific in-office days may be designated based on team needs and business priorities.
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.
Our Base Pay Range for this position
$127,200 - $212,000McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
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