Senior Scientist / Principal Scientist, Chemistry Lead

The Opportunity:

Does delivering a great small molecule development candidate thrill you?  We get excited, too, and we are building the best environment in the industry to discover the next generation of innovative therapeutics that will make a difference for patients. We are looking for a self-motivated, experienced Medicinal Chemist to join our team. You will work on exciting targets alongside some of the most talented scientists in a highly collaborative environment, while continuing to grow into better drug hunter.

Your Role:

• You will be responsible for developing and executing medicinal chemistry strategies on a lead optimization program to deliver a high-quality development candidate in a fast-paced environment.
• You will lead chemists at Relay as well as CRO teams to advance your project.
• You will work closely and collaboratively in a multi-disciplinary team of computational chemists, biophysicists, cell and molecular biologists, pharmacologists, and DMPK specialists. You see how all the aspects of compound performance are necessary to make it a drug, and you can communicate that effectively to your discovery partners.

Your background:

• PhD with at least 5 years or MS with at least 8 years of relevant biotech and/or pharmaceutical industry experience in medicinal chemistry, with an emphasis on lead optimization in small molecule drug discovery
• You were educated in chemistry with an emphasis on synthetic organic chemistry, synthetic methodology or a related field.
• You are passionate about working on high impact targets and bringing medicines to patients.
• You have led or are ready to lead a team and make critical decisions on the SAR direction.
• You have participated in the delivery of development candidates and your track record of excellence is supported by high impact, peer-reviewed publications and/or patents.
• You have good understanding of biology, pharmacology, DMPK and safety.
• You are comfortable enabling your compound design with in silico predictive tools and structure-based drug design.
• You have strong communication skills, can flex to different work styles, and believe that the best outcomes result from bringing out the creativity of your colleagues.
• You are committed to building an energetic, collaborative and open company culture and contributing to the company’s success. 

 

#BP1