Regeneron's Assay Development Group (ADG) in Bioanalytical Sciences, located in Tarrytown, NY, is seeking a Senior Principal Scientist. In this exciting role, you will create and execute novel assay strategies for all biotherapeutic modalities, designing experiments, troubleshooting problems, organizing and interpreting experimental results and performing follow-up experiments.
Develop bioanalytical assay approaches for pharmacokinetic, biomarker assays and immunogenicity assays for a diverse pipeline of novel biotherapeutics, including monoclonal antibodies, bispecifics, antibody-drug conjugates (ADC), adeno-associated virus (AAV), CAR-T, RNA as well as drug target biomarkers to support non-clinical and clinical studies.
Supervise a team of scientists in the development and validation of immunoassays for the measurement of drug, drug complexes and anti‑drug antibodies to support new programs.
Guides the designs and execution of immunoassays (PK, PD and ADA) by direct reports, based on protocols provided by literature, seminars and other scientists. Suggests troubleshooting experiments for assay-related problems follow-up experiments to further assay development and optimize assays.
Routinely reviews data for multiple developmental projects, working on these projects simultaneously.
Summarizes and presents results internally to management and externally in industry meetings.
Writes/reviews assay validation protocols, reports and SOPs prior to submission to Quality Auditing (QA). Functions as Study Director for assay validation studies conducted by direct reports.
Stimulates, develops, and promotes the scientific and career development of direct and indirect reports.
Can act as a leader within the group that effectively drives projects forward to meet aggressive timelines
Can communicate effectively with supervisor, upper management/senior leaders and other members within the company and/or outside vendors to obtain assay-related reagents or discuss reagents needs.
Propose innovative solutions and troubleshooting to address scientific complexity and challenges.
To be considered for this opportunity, you must have a PhD degree with 5+ or a MS with 8+ or a BS with 10+ years meaningful experience. An in-depth understanding of the science and technology on the development and validation of immunoassays is required. The ability to perform sophisticated technical tasks to pursue projects that incorporate a diverse set of skills and work on multiple projects/experiments simultaneously is helpful.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries’ specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually)