Scheduled Hours
40
Position Summary
Our current project is to understand the mechanisms underlying chronic inflammation in the progression of pre-cancerous states in the stomach and pancreas to cancer. We take a multi-focal approach to uncovering these mechanisms, relying on experimental systems in mice and from patient-derived gastric biopsies and gastric/pancreatic tumor resections. We apply transcriptional (i.e., single-cell and T cell receptor RNA sequencing), molecular (siRNA, CRISPR-Cas9), immunohistochemical, organoid, flow cytometric, and in vivo (i.e., mouse models) methods to develop new insight into the evolution of pre-cancerous stages to malignant lesions in the stomach and pancreas.
This position will specifically focus on processing blood, gastric biopsies, pancreatic fluid collections, and gastric/pancreatic tissue resections for downstream transcriptional and flow cytometric analyses. In addition, the candidate will be expected to isolate, derive, and maintain organoids from patient samples. Additional tasks will include preparing biopsies/tissue for histologic processing, isolating DNA/RNA and protein, and further characterization using molecular biology techniques (e.g., Western blotting, RT-PCR). The successful candidate will learn how to perform these tasks and will be expected to be honest, efficient, organized, and collaborative. The candidate will also be expected to learn any additional techniques relevant to the project. The candidate will communicate their findings with the Principal Investigators (PIs) on the project through regular meetings or formal presentations.
Provides critically complex research and experimentation for department/s allowing the advancement of scientific analysis and discovery. Serves as a subject matter expert offering support, training and guidance relative to the discipline/area. May participate and or present on the research developed, or the established work of those within the department.
Job Description
Primary Duties & Responsibilities:
Performs complex analyses, experiments and project work under general direction of the PI. Serves as representative for PI and ensures procedures and protocols are adhered to consistently and effectively meet department's standard. Exhibits a high degree of independent problem solving and ability to conduct research on assigned projects. May serve in lead role as needed.
Plans, develops, organizes and formalizes research results and findings. May develop for presentation and/or present on behalf of department. Conducts literature searches related to research projects. Writes/co-authors publications and/or papers supporting research findings in logical and sometimes multiple formats tailored to audiences. May participate in work related to grants.
Solves practical problems relating to difficulty with equipment or test subjects. Suggests technical/ procedural improvements in various methods. May develop and optimize experimental procedures and protocols. Provides high-level troubleshooting to advance process or lab procedures.
Serves as department's research representative and may participate in various related meetings and events. Gathers/delivers data/information and serves as subject matter expert. Performs statistical data analysis, as needed. Presents research information to internal and/or external audiences.
Organizes and maintains required documentation on lab and/or specimen conditions and can develop and summarize information into usable formats or presentations on behalf of the department. May communicate findings to various users or external audiences.
Performs all related work in accordance with established protocols and safety/compliance requirements.
May explain methods, lead or train other personnel or observers.
Working Conditions:
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Education:
Master’s degree or combination of education and/or experience may substitute for minimum education.
Certifications/Professional Licenses:
No specific certification/professional license is required for this position.
Work Experience:
Laboratory Setting (4 Years)
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
More About This Job
WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications/Professional Licenses:
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
No additional work experience unless stated elsewhere in the job posting.
Skills:
Critical Thinking, Detail-Oriented, Laboratory Instrumentation, Laboratory Research, Oral Communications, Recordkeeping, Self-Starter, Software Program, Spreadsheets, Statistical Software, Written Communication
Grade
R09
Salary Range
$41,700.00 - $75,600.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Personal
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Washington University is dedicated to building a community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.