Research Assistant 2

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The Neuro (Montreal Neurological Institute-Hospital) is a bilingual academic healthcare institution. We are a McGill research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. In order to better understand and find new treatments for neurodegenerative diseases, The Neuro has established an integrated ecosystem in which a number of R&D projects utilize patient-derived cells through a number of platforms, etc.

In the context of an exploratory project on Parkinson’s disease related to advancing iPSC-based models for study of neuro-immune aspects of the disease, the selected candidate,  working in the laboratory of Professor Edward A. Fon, will, under the direction of the immediate supervisor, plan and execute laboratory cell culture of human induced-pluripotent stem cells (iPSC), perform immunofluorescence experiments, and help with the analysis of scRNAseq data. They will perform differentiation protocols for generation of microglia and microglia-organoid assembloids. Then perform immunofluorescence experiments to further characterize these cultures. They will act as resource person for the supply of human iPSCs and microglia for subsequent analysis necessary to the project. They will contribute to writing a manuscript describing microglia-organoid assembloids for the study of Parkinson’s disease.

• Planning and executing iPSC culture within objectives set by supervisor.
• Performing specialized culture techniques such as generation of microglia, and microglia-organoid assembloids.
• Maintaining records and files.
• Acting as resource person and provide technical guidance and assistance concerning iPSC culture.
• Performing immunofluorescence experiments and confocal imaging to characterize assembloids.
• Helping with the analysis previously generated scRNAseq data to assess the impact of microglial integration on organoid cultures.
• Using a variety of equipment such as balances, pH meters, pipettors, laminar flow hoods, incubators, autoclaves, microscopes, spectrophotometers, centrifuges.
• The list of duties and responsibilities outlined above is representative and not a complete and detailed list of tasks which may be performed by an employee whose position has been matched to this generic job description.

OTHER QUALIFYING SKILLS & ABILITIES

• Experience in iPSC culture is highly recommended
• Experience in cell culture is mandatory
• Excellent organization skills
• French and English, spoken and written
• Digital competence

This position is covered by the AMURE collective agreement: http://www.aerum-amure.ca/wp-content/uploads/2023/07/AMURE-2023-2027.pdf

Before applying, please note that to work at McGill University, you must be both authorized to work in Canada and willing to work in the province of Quebec at the campus where the position is based / located.

McGill University is an English-language university where most teaching and research activities are conducted in the English language, thereby requiring English communication both verbally and in writing. The level of English required for this position has been assessed at a level #3 on a scale of 0-4.

$31.44

35 (Full time)

Montreal Neuro.

Professor

2026-01-05

2026-04-04

2025-12-03

This position is covered by the Association of McGill University Research Employees (AMURE) collective agreement.