Texas A&M

Postdoctoral Research Associate - Kirchner Lab

Bryan, TX Full time

Job Title

Postdoctoral Research Associate - Kirchner Lab

Agency

Texas A&M University Health Science Center

Department

Medical Physiology

Proposed Minimum Salary

Commensurate

Job Location

Bryan, Texas

Job Type

Staff

Job Description

Our Commitment 

Texas A&M University is committed to enriching the learning and working environment by promoting a culture that respects all perspectives, talents & lived experiences. Embracing varying opinions and perspectives strengthens our core values which are: Respect, Excellence, Leadership, Loyalty, Integrity, and Selfless Service.  

 

Who we are

As one of the fastest-growing academic health centers in the nation, Texas A&M Health encompasses five colleges and numerous centers and institutes working together to improve health through transformative education, innovative research and team-based health care delivery. 

What we want

The Postdoctoral Research Associate is responsible for conducting research into their field of expertise.  The Postdoctoral Research Associate will utilize the skills and expertise granted to them by their education and experience to complete research projects in their field of expertise. Writes and may contribute to research papers, articles, and publications. Assists with the preparation and cleaning of worksite. May collaborate with other researchers and/or faculty both within and outside of Texas A&M.

 

This position is within the Kirchner Laboratory in the Department of Medical Physiology at Texas A&M College of Medicine. This position will perform patch clamp electrophysiology, calcium imaging, and immunohistochemistry for to study the neurophysiology of vasopressin and oxytocin neurosecretory neurons, their role in hydromineral balance, and their dysfunction in a rat model of heart failure.

 

What you need to know

Salary: Will be commensurate based on the selected hire’s education and experience.   

Location/Schedule: Bryan, TX/ Full-Time; This position may require work beyond normal office hours and/or work on weekends.

Please note: This position is grant funded; future employment may be contingent upon future funding.   

Apply! Submitting a cover letter, CV/Resume to assist us with the review process. You may upload these documents on the application under CV/Resume. 

Required Education and Experience

  • Appropriate PhD in neuroscience, neurophysiology, or a related field.

Preferred Qualifications

  • Patch Clamp electrophysiology:

    • Prep solutions for recordings, cutting live brain slices on a vibratome, and perform voltage and current clamp recordings in neurons.

    • Use optogenetics, photolytic uncaging, chemogenetics, fluorescent biosensors, electrical stimulation, and application of pharmacologic compounds during patch clamp experiments.

    • Maintain the electrophysiology rig, keep accurate records of experiments, perform data analysis, and create figures for publications and grants.

  • Rodent survival surgery:

    • Coronary ligation (heart failure surgery) for studying the disease in electrophysiology experiments.

    • Stereotaxic delivery of AAVs encoding fluorescent tracers, DREADDs or opsins to be used in electrophysiology experiments.

  • Calcium imaging:

    • Utilize calcium dyes or genetically encoded calcium sensors (i.e. GCaMP) to measure and quantify intracellular calcium levels in a live brain slice preparation.

    • Perform these experiments simultaneously with patch clamp.

  • Immunohistochemistry (IHC)

    • Transcardial perfusion, fixation, cryostat sectioning, staining, and mounting tissue specimens.

    • Visualization and analysis of IHC imaging data

  • Multiunit electrophysiological experiments, particularly using Neuropixels

  • Software Expertise and Data Analysis:

    • pCLAMP, ImageJ, MatLab, Imaris

    • Additional expertise using Igor Pro, Prism, Python, and/or Adobe Illustrator

  • Ability to train other laboratory members in the techniques listed above.

Responsibilities

Research

  • Under general supervision, is responsible for conducting research into their field of expertise.

  • Utilizes knowledge and skills granted to them by their education and expertise to complete research projects in their field of expertise.

  • Assists with the preparation and cleaning of worksite.

  • Analyzes research data and summarizes results.

  • Writes and may contribute to research papers, articles, and publications.

 

Mentoring

  • May assist, mentor, and/or supervise student researchers and/or graduate students who are working on research related to the project.

 

Presentations

  • Prepares presentation materials on research topic that may be presented to small and/or large groups.

  • Actively participates in the preparation of required technical progress reports to research sponsors.

 

Professional Development

  • Apply for career-appropriate grants and fellowships under the guidance of the PI.

  • Travels to scientific conferences to give presentations.

 

Why Texas A&M University? 

We are a prestigious university with strong traditions, Core Values, and a community of caring and collaboration. Amenities associated with a major university, such as sporting and cultural events, state-of-the-art recreation facilities, the Bush Library and Museum, and much more await you. Experience all that a big city has to offer but with a reasonable cost-of-living and no long commutes. 

 

Instructions to Applicants: Applications received by Texas A&M University must either have all job application data entered, or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to prepopulate the online application. 

All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution’s verification of credentials and/or other information required by the institution’s procedures, including the completion of the criminal history check.

Equal Opportunity/Veterans/Disability Employer.