About the Opportunity
Job Summary
The Antibiotic Discovery Center (ADC) at Northeastern University seeks a Postdoctoral Research Associate to lead research in natural product drug discovery, including isolation, characterization, and mode-of-action studies of antibacterial compounds. The successful candidate will join a multidisciplinary team applying biochemical, microbiological, and analytical approaches to identify novel natural product scaffolds and elucidate their mechanisms.
Key Responsibilities
· Design and execute microbiological, biochemical, and genetic studies to identify and characterize novel natural products with antibacterial activity.
· Develop and optimize screening assays for natural product discovery, including bioassay-guided fractionation.
· Conduct mechanistic and mode-of-action studies using microbiological and biochemical tools.
· Lead compound isolation and structural characterization efforts in collaboration with chemistry teams.
· Mentor and train students and junior researchers in experimental techniques and data interpretation.
· Collaborate with internal and external partners to integrate discovery data and prepare publications and grant proposals.
· Present findings at internal meetings, conferences, and in peer-reviewed journals.
Qualifications
· Ph.D. in Microbiology, Biochemistry, Molecular Biology, Chemical Biology, or related discipline.
· Strong record of research productivity, evidenced by peer-reviewed publications.
· Demonstrated expertise in microbial genetics, natural product discovery, or bioassay development.
· Experience with chromatographic techniques, LC-MS, or NMR-based structure elucidation is advantageous.
· Excellent communication, organizational, and mentoring skills with a collaborative mindset.
About the Lab
The Antibiotic Discovery Center (ADC) at Northeastern University is an interdisciplinary research hub dedicated to discovering, characterizing, and developing novel antibiotics and bioactive natural products. The ADC integrates expertise in microbiology, biochemistry, chemical biology, and natural product chemistry to address the urgent global challenge of antimicrobial resistance. Researchers at the ADC work
collaboratively to identify new compounds from diverse microbial sources, elucidate their mechanisms of action, and advance them toward preclinical development through innovative screening, analytical, and genomic approaches.
Position Type
ResearchAdditional Information
Northeastern University considers factors such as candidate work experience, education and skills when extending an offer.
Northeastern has a comprehensive benefits package for benefit eligible employees. This includes medical, vision, dental, paid time off, tuition assistance, wellness & life, retirement- as well as commuting & transportation. Visit https://hr.northeastern.edu/benefits/ for more information.
All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law.
Compensation Grade/Pay Type:
108SExpected Hiring Range:
$59,425.00 - $83,935.00With the pay range(s) shown above, the starting salary will depend on several factors, which may include your education, experience, location, knowledge and expertise, and skills as well as a pay comparison to similarly-situated employees already in the role. Salary ranges are reviewed regularly and are subject to change.