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Dr. Yang Gao joined The Ohio State University (OSU) in August 2025 as an Assistant Professor in the Department of Cancer Biology & Genetics, where he is establishing an independent research program. Supported by generous start-up funding from OSU and an active NIH K99/R00 award, the Gao Lab provides a strong and stable foundation for scientific discovery. We are seeking 2 Postdoctoral Scholars to join our growing team and explore how tumor–immune interactions shape cancer progression and therapy response.
🔬 Our Research
At the Gao Lab, we study the tumor ecosystem with a focus on three major themes:
The heterogeneity of the immune landscape
Mechanisms of therapeutic resistance
The role of tumor–host interactions in cancer metastasis
Our work aims to uncover why treatment resistance and distant recurrence occur in solid tumors, with a special emphasis on breast cancer.
Our discoveries so far include showing how myeloid cell heterogeneity contributes to immunotherapy resistance and revealing how the bone microenvironment shapes breast cancer bone metastasis.
Current projects in the lab:
Exploring how neutrophil interferon-stimulated genes regulate the tumor immune microenvironment and response to immunotherapy. Mapping the immunosuppressive ecosystems that support breast cancer metastasis in major organs, including bone, lung, liver, and brain. Identifying new mechanisms that drive therapeutic resistance in metastatic disease.
To tackle these questions, we use cutting-edge technologies, including spatial transcriptomics, single-cell multi-omics, tumor immunology, and in vivo genetically engineered mouse models. By bringing these approaches together, we strive to generate insights that will translate into better therapies and improved outcomes for patients.
We Offer
✉️ How to Apply
Applications are reviewed on a rolling basis until positions are filled. Please include the following documents with your application:
A brief cover letter describing your background, research interests, and career goals
Curriculum vitae with publication list
Contact information for three references
Inquiries about this position can be directed to Dr. Yang Gao yang.gao@osumc.edu
Please include “Application for Postdoctoral Fellow + [Your Name]” in the email subject line.
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
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