Manufacturing Shift Associate (API)

API Manufacturing Shift Associate (Deputy Shift Leader)

College Park, Dublin

Full Time, Permanent (Shift based)

Introduction to role:

Are you ready to make a difference? At AstraZeneca, we're taking bold actions to revolutionize the way life-saving medicines are produced. Our new digital smart and paperless factory near Dublin, Ireland, is set to transform API manufacturing, enabling continuous production that delivers medicines faster, cheaper, and more sustainably. This cutting-edge facility will optimize our processes and enhance efficiency using advanced technology and digital innovations. Join us in this shift position where you'll engage in manufacturing activities and deputize for the Manufacturing Shift Lead when needed.

Accountabilities:

• Deputise for the Manufacturing Shift Lead where required - leading manufacturing teams, coordinating production activities, and acting as a plant representative in cross-functional groups.
• Instigate, explore, and evaluate opportunities to use technology – including AI, to improve production activities in the pursuit of next-generation processes including autonomous manufacturing.
• As a key member of the operations team, carry out multi-stage Active Pharmaceutical Ingredient (API) manufacturing processes in compliance with AstraZeneca, GMP & SHE standards.
• Provide operational expertise at accommodation meetings such as processing risk assessments.
• Reinforce standards required in terms of GMP, SHE, and specific product requirements.
• Set-up routings for production, changeover and cleans, and maintain relevant equipment to enable the smooth running of the plant unit.
• Receive, accept, locate, store, dispatch and deliver products and materials and complete all relevant documentation to meet GMP and SHE standards.
• Collaborate with the relevant function to receive and return the materials/components that feed into the production process.
• ERT membership will be included as a core responsibility.

Essential Skills/Experience:

• Minimum NFQ level 7 or equivalent in a scientific or engineering discipline (or able to demonstrate comparable proficiency) with history of positive application.
• High level of API, Pharmaceutical or other complex manufacturing experience, with skills to support planning, managing, and monitoring of major manufacturing production projects from concept to implementation.
• Ability to embrace and apply innovative engineering and digital technologies to drive enhanced production processes.
• Data driven to evaluate process performance and able to apply problem-solving skills to drive improvement opportunities.
• Able to drive improvement plans, priority setting, investigation reports, quality or performance improvement recommendations to completion.
• Able to make complicated judgements and anticipate future manufacturing production developments.
• Strong safety attitude, ensuring compliance against Safety, Health and Environment standards.
• Excellent Documentation Practices, GMP and regulatory knowledge/awareness.

Desirable Skills/Experience:

• Team or project management.
• Previous start-up experience.
• Documentation generation (drafting initial SOPs, MBR, LIMS sampling plans etc).
• Familiar with manufacturing systems e.g. Delta V.
• Lean qualification.
• Familiarity with Electronic batch record design and use.
• Experience in investigations, CAPA’s and change controls.
• Awareness and understanding of process equipment and TPM.

Why AstraZeneca?

At AstraZeneca's Operations function, we are leading an exciting time of growth and evolution. We pioneer new approaches and processes across our sites, empowering our teams to foster a Lean mindset and sustainable practices. Every change we make is to deliver better outcomes for our patients. We are inspiring and credible leaders, ensuring everyone on our site has a platform and opportunity to speak up and share their ideas. We are the champions of Lean, ensuring our teams understand and embody the benefits it can bring.

Our manufacturing sites are environments of constant and rapid change. It's a place to expect the unexpected. There's rarely an obvious answer to the varied challenges we face, so it takes adaptability, flexibility and patience to thrive here. We know our sites well and we understand our team's individual strengths and passions. It powers us to ensure they are each in the right place and empowered to succeed. Our work helps give people with diseases a fighting chance. Every day is a challenge but that's what keeps us going. There's an indescribable buzz when we get to meet patients we have helped!

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation!

Date Posted

18-Mar-2026

Closing Date

04-Apr-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.