Our purpose is to bring hope to life by enabling life-changing therapies for patients around the globe, creating a healthier and happier tomorrow. Our mission is to work side by side with our customers in order to improve patients’ lives by bringing new biopharmaceuticals to market.
Manufacturing Manager – Mammalian Downstream
Lead manufacturing performance where quality, people and execution meet
As Manufacturing Manager in Mammalian Downstream, you will take operational ownership of a key production area and ensure stable, compliant and efficient manufacturing performance across the week.
This is a role for a leader who can connect shift-based operations with business priorities, support functions and continuous improvement efforts. You will be close to daily execution, while also translating broader priorities into clear direction for your area.
You will lead a team of four Shift Supervisors and play an important role in ensuring that production runs seamlessly across shifts always with safety, quality and delivery as the foundation.
Turning strategy into strong daily execution
Your success in this role will come from creating clarity, flow and accountability across shifts. You will own the performance of your production area, ensuring that output, quality and compliance are continuously monitored and improved.
You will work closely with support functions such as Quality, Engineering and Supply Chain to ensure production readiness, resolve issues effectively and keep rooms, equipment and processes fit for purpose. A key part of the role is to identify risks early, act proactively and drive weekly operational alignment across the organization.
You will also represent your area in audits, inspections and client visits when required, bringing both operational insight and leadership presence into important cross-functional settings.
Leading leaders in a complex GMP environment
In this role, you will lead, coach and develop a team of Shift Supervisors, ensuring strong and consistent first-line leadership across shifts.
You will set clear expectations for performance, accountability and leadership behavior, while building engagement, team effectiveness and a strong culture of ownership. The role also includes handling complex people and performance matters and owning core HR processes such as performance reviews, goal setting, development and workforce planning.
This is a hands-on leadership role where you will need to balance people leadership with operational accountability and stay calm and decisive when priorities shift or pressure increases.
Strengthening quality, compliance and continuous improvement
You will ensure full compliance with GMP, SOPs and safety standards across all shifts. At the same time, you will lead and support deviation handling, investigations and root cause analysis.
A central part of the role is to identify systemic issues and implement sustainable solutions that improve performance, robustness and efficiency in your area.
What you bring
We are looking for someone with strong technical understanding of biologics API manufacturing and the leadership capability to turn plans into reliable execution.
You have:
Experience from multi-shift manufacturing environments, CDMO or complex production setups, as well as exposure to audits and regulatory inspections, will be an advantage.
The leadership profile we value
You are a visible leader who creates clarity and direction. You work in a structured and performance-driven way, with a hands-on mindset and the ability to collaborate effectively across functions.
You know how to balance people leadership with operational accountability, and you bring strong decision-making capabilities when complex situations need to be solved.
Our culture at AGC Biologics is defined by the six core values: Knowledge, Trust, Quality, Ingenuity, Accountability and Teamwork. Our core values stem from our team members and are embedded into our DNA. They provide a common language and understanding of how we as an organization are connected across three continents. Our core values serve as a compass and reminder of how we achieve our purpose of bringing hope to life for patients around the globe.
AGC Biologics is a leading global biopharmaceutical Contract Development and Manufacturing Organization (CDMO) with a strong commitment to delivering the highest standard of service as we work side-by-side with our clients and partners, every step of the way. We provide world-class development and manufacture of mammalian and microbial-based therapeutic proteins, plasmid DNA (pDNA), messenger RNA (mRNA), viral vectors, and genetically engineered cells. Our global network spans the U.S., Europe, and Asia, with cGMP-compliant facilities in Seattle, Washington; Boulder and Longmont, Colorado; Copenhagen, Denmark; Heidelberg, Germany; Milan, Italy; and Chiba, Japan. We currently employ more than 2,500 employees worldwide. Our commitment to continuous innovation fosters the technical creativity to solve our clients’ most complex challenges, including specialization in fast-track projects and rare diseases. AGC Biologics is the partner of choice. To learn more, visit www.agcbio.com. Want to keep posted about our growth and learn more about our company? Follow us on LinkedIn and give us a quick Like on Facebook!
AGC Biologics offers a highly competitive compensation package and a friendly, collaborative culture that values personal initiative and professional achievement. AGC Biologics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, color, family or medical care leave, gender identity or expression, genetic information, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran status, race, religion, sexual orientation, or any other characteristic protected by applicable laws, regulations and ordinances.