Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
Global Impact: Contribute to therapies that make a lasting impact on patients globally.
We are seeking Manufacturing Associates of various levels to support our CMC-GMP Manufacturing team. The Manufacturing Associate will be responsible for supporting clinical manufacturing by performing specialized, time-sensitive cell processing and testing procedures on patient-derived cellular products. This role ensures compliance, product integrity, sterility, and accurate documentation in accordance with regulatory and quality standards.
Level and scope of responsibility will be determined based on education, experience, and demonstrated technical expertise.
FLSA Classification: Hourly, Non-Exempt
Schedule: 0800 - 1700 or 1230 - 2100; Monday to Friday; On-site
Reports to: Manufacturing Manager
Location: 13203 Murphy Road Suite 100 Stafford, TX 77477
What You’ll Do:
As a Manufacturing Associate, you will play a key role in supporting manufacturing operations:
Core Manufacturing Responsibilities
Serve as operator and/or verifier for cell growth and manipulation procedures, including cell enrichment, culture, cryopreservation, thawing, and washing
Perform manufacturing activities in compliance with FDA Good Laboratory Practices (GLP), Good Manufacturing Practices (GMP), Good Tissue Practices (GTP), and standards including FACT, CAP, and CLIA
Adhere to ALCOA++ and cGDocP requirements while maintaining accurate, compliant documentation and batch records
Ensure aseptic handling of reagents and cellular products to maintain sterility and integrity through final patient infusion
Follow strict cleanroom gowning and environmental procedures (Grade A/B/C/D environments)
Identify and document deviations/events, notify leadership and Quality in a timely manner, and support root cause investigations and CAPAs
Work productively in a highly collaborative, creative, and fast-paced manufacturing environment
Secondary / Operational Support Functions
Independently perform calculations for cell viability, dilutions, and concentrations
Complete required logs, trackers, and documentation accurately
Maintain GMP cleanliness (autoclaving, waste handling, facility organization)
Support donor evaluation knowledge, screening/testing requirements, labeling, product acceptability, and release criteria
Support validation and study activities (IQ/OQ/PQ)
Provide input on change controls, work instructions (WIs), SOPs, deviations, OOS/OOE investigations, reports, and CAPAs
Perform routine equipment maintenance and troubleshooting
Prepare and present manufacturing summaries, as applicable
Additional Responsibilities by Level
MA II: Demonstrates increased independence, technical proficiency, and ability to serve as verifier; contributes to process improvements and troubleshooting.
Senior MA: May lead manufacturing runs, mentor junior staff, assist with training, and drive continuous improvement initiatives.
Required Experience and Education:
Manufacturing Associate I
Associate degree (or enrollment) in Biology, Biotechnology, Biomanufacturing, or related field
0–2 years of relevant experience
Manufacturing Associate II
Associate or Bachelor’s degree in related scientific field
2+ years of GMP or cell therapy manufacturing experience
Senior Manufacturing Associate
Bachelor’s degree preferred
4+ years of GMP or cell therapy manufacturing experience
Demonstrated technical leadership and advanced troubleshooting capability
Competencies:
Independent Working- routine tasks with limited supervision; non-standard tasks with close supervision.
Communication- clear and efficient verbal and written communication; common courtesy; interaction mainly limited to own team (peers and supervisor)
Problem Solving- ability to identify, deeply analyze and communicate problems; basic ability to develop suitable solutions.
Critical Thinking- basic reflection on standard processes; identification of basic need and room for improvement within own or narrow scope.
Initiative- high degree of initiative and intrinsic motivation to exceed basic expectations of own tasks and responsibilities.
Organizational & Prioritization Skills- basic organization skills required to structure own daily tasks according to predefined work packages, schedule and standard lab processes; prioritization in close interaction with supervisor.
Coachability- receive pre-defined trainings essential for area of responsibility; high responsiveness to constructive criticism and basic ability to autonomously reflect on required improvements; timely implementation of suggested improvements.
Leadership Skills, Training & Supervision- basic leadership skills required for on-the-job trainings and guidance/support of (new) team members (e.g. providing and receiving feedback, empathy, honesty, reliability); train, instruct and coordinate E level; train D & C level during onboarding.
Work Environment:
This position works in a typical office and/or clinical lab environment with moderate noise levels and uses phone, computer, office equipment and supplies on a regular basis. While performing the duties of this job, the employee is occasionally exposed to moving mechanical parts, fumes or airborne particles, pathogens and toxic or caustic chemicals. The employee is occasionally exposed to wet and/or humid conditions, risk of electrical shock, sharps, or cuts, while performing tests.
Typical office environment with moderate noise levels (~20% of work hours).
Uses phone, computer, office equipment and supplies on a regular basis.
cGMP clean room spaces and facilities (~80% of work hours).
Grade A/B/C/D GMP environment with associated facility noise levels.
Uses cleanroom phone, computer, variety of equipment and reagent/supplies.
General unclassified laboratory spaces, as needed.
Common laboratory equipment and noise levels.
While performing the duties of this job, the employee routinely handles blood components and is occasionally exposed to temperatures between -196°C and 40°C, liquid nitrogen, liquid nitrogen vapor, dry ice, and carbon dioxide.
Physical demands:
Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly.
Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds.
Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.
Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or arms but may occur on the shoulder.
Near Visual Acuity – clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).
Pushing - Exerting force upon an object so that the object moves away from the object.
Pulling - Exerting force upon an object so that the object moves toward the force.
Sitting – remaining in a sitting position for at least 50% of the time.
Standing/Walking - remain on one's feet in an upright position at a workstation.
Stooping – occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles.
Work authorization/security clearance requirements:
Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment
Affirmative Action/EEO statement:
Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, color, religion, national origin, ethnicity, marital status, age, physical or mental disability, medical conditions, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.”
What do we offer?
At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics
Comprehensive Benefits:
Competitive rates for Health, Dental, and Vision Insurance
4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
Sick Time Off – 56 hours
12 Paid Holidays
100% Employer-Paid Life Insurance up to at 1x annual salary, up to one hundred thousand (club together)
100% Employer Paid Short- and Long-Term Disability Coverage
401(k) with Immediate Eligibility & company match…
You are eligible for 401(k) plan participation as of your first paycheck.
The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
Partially paid Parental Leave for eligible employees. (3 weeks)
Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.
Professional Growth:
Opportunities to work with leading experts in the field of T-cell immunotherapy.
Company provided learning and development opportunities
Fast paced, high demand collaborative and dynamic environment.