Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here at BMS with our Cell Therapy team.
The Manager, CAR T Value Stream Cryo Operations leads a team of Specialists, Team Leads and Associates responsible for all processes associated with Cryopreservation and Sample Management, Frozen Process Material Retrieval, Movement, and Storage within CAR T clinical and commercial operations in a cGMP multi-cleanroom suite. This role plays a critical part in ensuring production continuity, traceability, and compliance across multiple shifts in a 24/7 operation. The Manager, is accountable for driving operational excellence, ensuring compliance with all regulatory requirements (FDA, DEA, DOT, ISBT, CTPAT, OSHA, VAWD, cGMPs), and fostering a culture of safety, collaboration, innovation, and continuous improvement.
Shift Available:
Wednesday - Saturday (with e/o Wednesday off), Onsite Overnight Shift, 5 p.m. - 5:30 a.m.
Responsibilities:
Lead Cryopreservation and handling of all Cell Therapy Products across multiple production areas and shifts.
Ensure execution of production tasks in alignment with cGMPs, SOPs, and Work Instructions while maintaining complete traceability.
Oversee Material Retrieval, Movement, Storage, and Inventory Management within Cryotanks and Controlled Rate Freezers (CRFs).
Maintain hands-on expertise in Unit Operations, role model good execution and behaviors, and backfill resources if needed.
Provide production scheduling team with daily, weekly, and monthly updates on resource availability and task execution.
Lead batch record reviews (BRR) and ensure all documentation follows ALCOA+ principles.
Drive adherence to all training requirements, ensuring team members are proficient and qualified.
Recruit, train, and develop a high-performing team of Managers, Leads, and Associates.
Set and adjust team priorities to align with site and functional objectives.
Conduct regular 1:1 meetings to mentor and support team members’ professional development.
Own the performance review process, provide continuous feedback, and recognize achievements.
Foster a culture of accountability, ethics, and decision-making within the team.
Champion lean principles to improve efficiency and eliminate non-value-added activities.
Lead troubleshooting activities and own Deviation Management, ensuring timely documentation and closure.
Monitor deviation metrics, identify repeat causes, and drive corrective actions.
Participate in projects, change controls, and CAPAs to enhance compliance and operational performance.
Participate and lead in process improvement projects withing the department.
Build strong cross-functional relationships to drive collaboration and alignment with stakeholders.
Control operational expenses (OT, Supplies, T&E) and identify cost-saving opportunities.
Take personal responsibility for safety and hold the team accountable for safe practices.
Perform regular safety Gemba walks, identify hazards, and drive corrective actions.
Lead and participate in Tier 1/2/3 meetings, ensuring clear communication and problem resolution.
Promote a culture of right-first-time execution, proactive issue resolution, and continuous learning.
Champion a culture of compliance, operational discipline, and continuous improvement.
Lead by example, demonstrating BMS core values: Inclusion, Accountability, Innovation, Urgency, and Passion.
Drive root cause analysis and sustainable corrective actions to prevent recurrence of issues.
Act as a change agent, promoting flexibility, creativity, and accountability in a fast-paced environment.
Ensure knowledge sharing and cross-training across teams to build expertise.
Knowledge & Skills:
Advanced knowledge of cGMP/GDP/Pharmaceutical regulations and applications.
Advanced knowledge of cryopreservation, material handling and logistics including best industry practices, application of principles, concepts, practices, standards, validation, and qualification.
Strong knowledge and application of OSHA, DEA, USP and other applicable WH regulations.
Proficiency in ERP systems / WMS Applications, MES and analytics tools.
Proficiency in system and application use for business operations.
Proficiency in MS Office applications.
Proficiency in analytical, problem-solving, critical thinking skills and strong situational decision making.
Proficient organizational and time management skills.
Strong written and verbal communication skills.
Intermediate presentation development and delivery skills.
Ability to adapt to changing business conditions while maintaining appropriate level of controls and compliance with regulatory requirements.
Ability to travel 10% of time.
Basic Requirements:
Bachelor’s degree in a relevant field (Life Sciences, Engineering, Operations). An equivalent combination of education and working experience to be considered.
5+ years of experience in biopharmaceutical manufacturing, cell therapy, or GMP operations.
2 years of leadership experience managing teams.
Strong knowledge of cryopreservation, GMP documentation, and deviation management.
Experience driving lean manufacturing principles and continuous improvement initiatives.
BMSCART, #LI-Onsite
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Compensation Overview:
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.
Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:
Health Coverage: Medical, pharmacy, dental, and vision care.
Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
Work-life benefits include:
Paid Time Off
US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
Supporting People with Disabilities
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
Candidate Rights
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Data Protection
We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.
R1597706 : Manager, Value Stream Cryo Operations