Lead Analytical Monitor

Lead Analytical Monitor South Africa

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

We are currently seeking an Analytical Monitor (Advanced Level) to join our dynamic and expanding client-dedicated Integrated Data Analytics & Reporting team. In this role, you will play a pivotal part in enabling proactive, data-driven risk identification at both site and subject level, directly supporting clinical trial integrity, patient safety, and operational efficiency.

As an Advanced Analytical Monitor, you will work across multiple mid to high-complexity studies, delivering deep analytical insights, supporting innovation, and collaborating closely with global cross-functional partners across Data Management, Central Monitoring, and Site Management. You will also provide mentorship to junior colleagues, contributing to the growth and excellence of the wider team.

What you will be doing

• Performing analytical monitoring activities for assigned clinical trials, ensuring early identification of site- and subject-level risks, trends, and data quality issues.
• Conducting regular, fit-for-purpose site/subject-level data reviews to detect early warning signals and prevent issue recurrence.
• Accessing and analysing data from multiple systems, reporting tools, platforms, and databases to derive insights that support informed decision-making.
• Collaborating closely with Site Managers, Central Monitoring, and other cross-functional partners to influence site prioritisation and guided risk management.
• Ensuring all activities are conducted in full compliance with relevant SOPs, ICH-GCP requirements, regulatory standards, and project timelines.
• Communicating effectively across multiple stakeholders, managing parallel workstreams, and escalating issues through established pathways.
• Providing training, guidance, and mentoring to junior Analytical Monitors to support capability development across the team.

Your profile

• Bachelor’s degree in Health Sciences, Data Sciences, or a related discipline; a Master’s degree is preferred.
• Approximately 4+ years of experience within the Pharmaceutical, Biotech, or CRO industry.
• Strong understanding of clinical trial operations, study execution, and data flow within clinical research.
• Demonstrated experience in data analysis within a clinical research environment, including familiarity with core statistical concepts.
• Project, issue, and risk management experience, with the ability to apply critical thinking to drive solutions and support decision-making.
• Experience working with technology platforms and systems used for clinical data collection, analysis, and reporting.
• Excellent communication and interpersonal skills, with the ability to collaborate effectively across global cross-functional.
• Strong organisational skills, with the ability to manage multiple priorities in a fast-paced environment.
• Excellent verbal and written communication skills in English.

What ICON can offer you:

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values.   We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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