Global Medical Affairs Leader, CardioRenal

Are you ready to make a significant impact in the world of healthcare? As the Global Medical Affairs Leader (GMAL) for CardioRenal at AstraZeneca, you will report directly to the Global Medical Head of CardioRenal. This pivotal role combines your medical expertise with insights from markets, healthcare professionals, patients, and health systems to develop and execute world-class medical strategies for AstraZeneca medicines globally. As a key member of the Global Medical Team, you will serve as a strategic partner and leader, bridging the Global Product Team and Regional Medical teams across major markets. Your efforts will ensure alignment with marketing company affiliates, healthcare professionals, and patients through ambitious global product and disease area strategies. Are you ready to transform health systems, conduct practice-defining studies, and accelerate the delivery of clinical trials?

Accountabilities:

• Launch & Performance: Lead the delivery of prerequisites for an outstanding product launch—including strategy, scientific narrative, and key performance indicators (KPIs)—with the ability to critically assess performance and proactively implement actions.
• Scientific Leadership: Shape, communicate, and champion world-class medical content and compelling science narratives that support products and key market-shaping initiatives.
• Evidence Generation: Demonstrate proven experience designing and delivering clinical trials or real-world evidence programs. Shape the global evidence strategy by translating insights into innovative clinical research and observational studies, differentiating or expanding market access for AstraZeneca medicines, and supporting healthcare change initiatives. Partner with global and affiliate teams to identify and address evidence gaps that drive product value and patient outcomes.
• Innovator: Identify and create new opportunities to accelerate market growth and impact, scale best practices globally, and pilot innovative approaches to medical strategy and health system engagement.
• External Scientific Engagement: Drive a visible and credible scientific engagement agenda—actively partnering with international key thought leaders, societies, health organizations, and health system decision-makers to ensure AstraZeneca’s voice and science lead the conversation.
• Business Partner: Collaborate with internal functions (Evidence Generation, Medical Information, Publications, Market Access, Commercial, and R&D) to ensure strategic alignment and delivery of high-impact medical resources, as well as ensuring scientific and regulatory compliance in all communications and activities.

Essential Skills/Experience:

• Doctoral-level degree (MD, PhD, PharmD) in a relevant discipline.
• 3-5 years of experience in the pharmaceutical industry (Medical, Marketing, R&D, Market access roles), or experience working within a relevant health system setting (clinical, pharmacy, pathway design, etc.)
• Proven ability to lead end-to-end medical strategy pre- and post-launch, including defining evidence plans, translating data into persuasive scientific narratives, aligning and mobilizing cross-functional teams, and shaping external stakeholder understanding and adoption.
• Strong analytical and strategic thinking skills, with the ability to translate complex data into actionable insights and compelling value propositions for patients, payers, and providers.

Desirable Skills/Experience:

• MBA
• Recognized expertise in the relevant or related therapeutic area.
• Prior experience leading the design, execution, and interpretation of interventional clinical trials or real-world evidence studies (such as registries, pragmatic studies, or health outcomes research). Deep medical expertise in the relevant disease area, evidenced by prior hands-on clinical or research experience.
• Experience operating successfully in complex, matrixed organizational environments.
• Successful track record of launching new products or indications.
• Established relationships with global clinical thought leaders, professional societies, and healthcare organizations.
• Advanced collaboration and networking skills—internal and external.
• Experience working on global evidence generation programs, such as clinical trials (phase II/III/IV) and/or real-world evidence studies.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers an unparalleled opportunity to be at the forefront of healthcare innovation. As part of our dynamic BioPharmaceuticals team, you'll contribute to shaping the future of medical practices while addressing unmet patient needs. Our collaborative environment fosters growth and development, allowing you to leverage your scientific knowledge alongside business acumen. With a rich pipeline and a commitment to transforming healthcare, AstraZeneca is where you can make a meaningful impact on patients' lives.

Ready to take the next step in your career? Apply now and join us in making a difference!

The annual base pay for this position ranges from $193,281 to $289,922. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Date Posted

17-Dec-2025

Closing Date

08-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.