FSP - Sr. Scientist - Organic Chemistry

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

This is a fully onsite role based at our customer’s site in San Diego, CA. We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate.

Must be legally authorized to work in the United States without sponsorship.

Must be able to pass a comprehensive background check, which includes a drug screening.

Key responsibilities:

Coordinates kilo lab operations, chemical manufacture, and site readiness including equipment identification, qualification and maintenance. A partner for scientists in preparing batch records, adapting processes for scale-up, hands-on manufacture, engineering solutions required for safe and efficient small molecule and peptide operations. Will also provide support of process development activities and systems development for operations including platforms. Will provide training to junior staff for operations at kilogram scale.

• Assists in all facets of chemical process development from small scale synthesis to scale-up manufacturing during API development
• Supports the technology transfer (chemical process, analytical methods) for manufacturing activities into the Neurocrine kilo laboratory
• Participates as a key member of cross-functional development teams to effectively meet science and business-critical objectives related to API manufacture
• Participates in internal project team meetings ad-hoc to ensure readiness for internal scale-up
• Performs authoring and review of manufacturing protocols, reports, and batch records
• Collaborates with multiple functional lines (Pre-clinical, Clinical, CMC, Regulatory, Quality Assurance, Commercial) within the company
• Provides logistical and scientific support for process development for API projects and projects of limited scope, such as solid-state form and catalytic process screening as well as new technology endeavors deemed of interest
• Maintains the kilo lab and equipment, serves as an expert in set up and operations
• Other duties as assigned

Education and Experience:

• Bachelor's degree in lab sciences such as Organic Chemistry, Chemistry or similar
• Sr. Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years’)
• OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
• OR PhD

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

Common Knowledge & Skills:

• Advanced knowledge and demonstrated ability to work with chemical synthetic equipment and execute chemical processes
• Ability to work as part of and when needed may lead teams
• Exhibits leadership and significant knowledge related to synthetic scale-up, typically guides lower level and/or indirect teams in kilo lab manufacture
• Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency

Job Specific Knowledge & Qualifications:

• Capable to serve as internal lead for process scale-up programs
• Trained in a scientific discipline and understands the scientific method
• Specific knowledge of Pharmaceutical CMC related process chemistry, solid state material properties/manipulations and analytical techniques necessary to develop and manufacture API
• Familiarity with regulatory and quality aspects of CMC and API activities and documentation
• Ability to think creatively and be a team player
• Offer flexibility with a willingness to work on multiple projects simultaneously

Working Environment:

Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

Able to work upright and stationary and/or standing for typical working hours.

Able to lift and move objects up to 25 pounds

Able to work in non-traditional work environments.

Able to use and learn standard office equipment and technology with

proficiency.

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Benefits

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!

Compensation and Benefits

The salary range estimated for this position based in California is $90,027.00–$100,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards