Bioprocess Engineer III

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Cold Room/Freezers -22degreesF/-6degrees C, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Strong Odors (chemical, lubricants, biological products etc.), Will work with hazardous/toxic materials

Job Description

As a member of the Bioprocessing Collaboration Center you will develop and drive implementation of innovative upstream and downstream bioprocessing solutions! Act as technical lead on multiple projects. Investigate, create, and develop new scientific methodologies in a cross company team environment. Evaluate and contribute to the evidence generation of Single Use Technology (SUT) and supporting systems including automation and process analytical technologies.

Test novel bioreactors, and develop new downstream processing equipment to enhance process intensification and continuous processing strategies. Drives early adoption of new technologies at both PSG internally as well as to leading biotechnology companies externally.

Areas of focus

As a team, we collaborate on experiments showcasing the capabilities and benefits of Thermo Fisher’s technologies! Serve as in-house technical experts in applied biotechnology and process development by working with Process Development and Manufacturing groups to solve process challenges.

As an individual you will conduct sophisticated analyses to support testing and development of SUT systems. Record results in electronic notebook accurately, clearly, and regularly, and reviews documentation by others. Summarize results by preparing internal and external materials such as presentations, protocols, reports, and white papers. Communicate results to people with both technical and non-technical backgrounds.

We also effectively network with colleagues from Bio Design Centers (BDC) and R&D sites globally to build effective shared technical resources and remain current in the field by review of relevant scientific literature and attendance at appropriate scientific seminars and conferences. May travel up to 25% as the need arises

Education/ Experience

• B.S. in Chemical Engineering, Biomedical Engineering, Biochemistry, Biology or related field with 4+ yrs, Masters with 2+ yrs, equivalent combinations of education, training, and work experience may be considered.
• Experience with performing standard upstream unit operations (Fed-batch and perfusion cell culture) at bench and pilot scale, including AMBR systems.
• Experience with performing purification unit operations (column chromatography, ultrafiltration/diafiltration) at the bench or pilot scale, including AKTA systems
• Experience with HPLC-based protein analytics and online PAT experience preferred

Knowledge, Skills, Abilities

• Advanced and deep knowledge of multifaceted aspects or a specialized aspect of Single Use Technologies and solid understanding of principles of cell culture, including perfusion.
• Understanding of downstream process principles and the ability to assist with evaluating purification performance, interpreting process trends, or contributing to method improvements
• Excellent problem solving and critical thinking skills. Excellent writing, communication and presentation skills. Strong MS Excel experience. Excellent organization and planning skills.
• Ability to design complex studies and to analyze and summarize scientific data. Ability to author reports, procedures, and other documents. Experience with DOE is preferred.
• Ability to lead and mentor less experienced staff.
• Ability to function in a constantly evolving cross company matrixed environment.