Senior Director, Architecture – Enterprise and Strategy, Alexion

Shape the Future of Enterprise Architecture with AI at Alexion

At Alexion, part of AstraZeneca, we are reimagining how technology powers life-changing medicines. As Senior Director, Architecture, you will lead the strategic design and evolution of our enterprise architecture, driving transformation across business and IT landscapes. This is not just a leadership role—it’s a chance to define how AI and advanced analytics reshape the way we deliver value to patients worldwide.
 

Our Mission:
We are driven to transform the lives of people affected by rare diseases and devastating conditions through the development and delivery of life-changing medicines. Your work will enable this mission by creating a technology foundation that accelerates innovation and improves patient outcomes.
 

Why this role matters:
Enterprise Architecture is at the heart of our digital strategy. With AI accelerating innovation, this role is critical to ensuring our architecture is future-ready—enabling agility, scalability, and data-driven insights across the organization. You will champion standards, patterns, and roadmaps that unlock AI-powered capabilities, guiding Alexion toward a smarter, more connected enterprise.
 

What you’ll do:

• Set the vision and strategy for enterprise architecture, aligning with business priorities and AI-driven transformation.
• Define and enforce architecture standards, patterns, and roadmaps across cloud, data, and application domains.
• Partner with senior business and IT leaders to integrate AI into architecture blueprints, enabling predictive analytics and intelligent automation.
• Lead a team of architects to deliver end-to-end solutions that simplify complexity and accelerate innovation.
• Act as a strategic advisor on architecture decisions, ensuring compliance, cost efficiency, and adoption of emerging technologies.
• Drive continuous improvement of architecture capabilities, fostering best practices and thought leadership.
   

Essential requirements:

• Minimum bachelor’s degree in computer science, engineering, information technology or equivalent
• + 10 experience in Enterprise Architecture leadership roles.
• Expertise in cloud-native strategies (AWS, Azure, MultiCloud) and data architecture.
• Strong understanding of AI, machine learning, and data modeling technologies.
• Proven ability to influence senior stakeholders and deliver transformation at scale.
• High emotional intelligence, adaptability, and strategic vision.
   

Why join us?

At Alexion, you’ll work in a collaborative, fast-paced environment where bold thinking meets cutting-edge technology. We offer competitive compensation, comprehensive benefits, and the opportunity to make a real impact on patients’ lives.
 

Ready to lead the future of architecture with AI?

Apply now and be part of a team that’s transforming healthcare through technology.
 

The annual base pay for this position ranges from $182 516,00 to $​273 774,00 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
 

Technology at AstraZeneca is a home for purposeful disruptors!  

Date Posted

13-nov.-2025

Closing Date

27-nov.-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.