Prolific Machines is ushering in a new era of biotechnology with light. Our mission is to make next-generation therapies broadly available to patients. Our first-of-its-kind Photomolecular Platform uses light to precisely guide how cells produce complex biologics, enabling higher titers, improved quality, and faster development timelines. By helping partners overcome today’s manufacturing bottlenecks, we’re accelerating the delivery of life-changing medicines. Prolific is supported by leading investors, including Bill Gates’s Breakthrough Energy Ventures, Mayfield, and SOSV.
Help us create a brighter tomorrow with biology. We're looking for mission-driven, talented, and kind people to join our team.
We are looking for a highly motivated and detail-oriented RA II or Sr. RA to drive mammalian cell culture-based protein production workflows at Prolific. We are a team of scientists using light to control the expression of biotherapeutic proteins, increasing titer and improving quality attributes. We are rapidly expanding our capabilities in mammalian cell line engineering, stable cell line generation, and driving production runs to produce therapeutic proteins. You will be instrumental in optimizing and executing cell line development and protein production which will support multiple projects. Your responsibilities will include maintenance and engineering of mammalian suspension cell lines (including CHO), handling, seeding, and sampling runs for protein production, and contributing to downstream readouts such as Octet BLI, flow cytometry, and metabolite measurements (such as Nova). Your knowledge of mammalian cell line development techniques, combined with your attention to detail and motivation to learn will make you highly effective in this role. The ideal candidate for this role is energized by hands-on technical work and takes pride in owning and refining routine cell line generation processes for high quality results. You’ll get to work cross collaboratively with team members in optogenetics, synthetic biology, cell line development, hardware engineering, bioprocessing, and data science disciplines to establish cell lines crucial to Prolific’s success. This is a unique position and opportunity to drive cell culture workflows in an exciting startup setting. You’ll be provided with room for technical growth and receive mentorship to help you succeed. This role is based on-site in our headquarters in Emeryville, CA.