Texas A&M

Postdoctoral Research Associate

Bryan, TX Full time

Job Title

Postdoctoral Research Associate

Agency

Texas A&M University Health Science Center

Department

Cell Biology and Genetics

Proposed Minimum Salary

Commensurate

Job Location

Bryan, Texas

Job Type

Staff

Job Description

Our Commitment    

Texas A&M University is committed to enriching the learning and working environment by promoting a culture that respects all perspectives, talents & lived experiences. Embracing varying opinions and perspectives strengthens our core values which are: Respect, Excellence, Leadership, Loyalty, Integrity, and Selfless Service.  

 

Who we are

As one of the fastest-growing academic health centers in the nation, Texas A&M Health encompasses five colleges and numerous centers and institutes working together to improve health through transformative education, innovative research and team-based health care delivery. 

What we want

The Postdoctoral Research Associate is responsible for conducting research into their field of expertise.  The Postdoctoral Research Associate will utilize the skills and expertise granted to them by their education and experience to complete research projects in their field of expertise. Writes and may contribute to research papers, articles, and publications. Assists with the preparation and cleaning of worksite. May collaborate with other researchers and/or faculty.

What you need to know

Salary: Will be commensurate based on the selected hire’s education and experience.   

Location: Bryan, TX

Please note: This position is grant funded; future employment may be contingent upon future funding.   

Apply! Submitting a cover letter, resume/CV to assist us with the review process. You may upload these documents to the application under CV/Resume.

Required education and experience

  • Ph.D.  in Biological Sciences, Neuroscience, or related degree area.

Physical Requirements

  • Ability to work in BL2 laboratories

  • Ability to work in the vivarium performing experiments on rats and mice.  

Preferred qualifications

Experience in the following

  • Single-cell and single-nuclei RNA sequencing studies and the associated bioinformatics analysis

  • Proteomic studies and data analysis

  • LCMS and RNAi studies

  • Gut Microbiome analysis to understand Gut-Brain Signaling

  • Performing brain tissue analysis involving immunohistochemical and immunofluorescence staining, confocal microscopy, ELISA, WB, and qPCR studies.

  • Performing mouse and rat neurobehavioral tests

  • Measuring therapeutic effects of intranasal extracellular vesicle treatment in animal models of disease using various neurobehavioral tests

  • Performing brain tissue analysis involving immunohistochemical and immunofluorescence staining, confocal microscopy, ELISA, WB, and qPCR studies.

  • Preparing cultures of pluripotent stem cells, neural stem cells, various neural cells (neurons, astrocytes, oligodendrocytes)

  • Isolation and characterization of extracellular vesicles from culture media and plasma using size-exclusion chromatographic methods, in vitro assays, RNAi studies.

  • Culturing of brain organoids

  • Strong background in bioinformatics

Responsibilities

Research:

  • Under general supervision, is responsible for conducting research into their field of expertise.

  • Stem Cell and neural cell culturing;

  • Isolation and engineering of extracellular vesicles;

  • Single-cell and single-nuclei RNA sequencing studies and the associated bioinformatics analysis;

  • Proteomic studies and data analysis;

  • Gut Microbiome analysis;

  • Perform mouse and rat neurobehavioral tests

  • Measure therapeutic effects of intranasal extracellular vesicle treatment in animal models of disease using brain tissue analysis;

  • These will involve immunohistochemical, immunofluorescence, ELISA, WB, and qPCR studies on brain tissue samples to measure the expression of various proteins, mRNAs, and miRNAs.

  • Prepare cultures of neurons and glia, perform immunohistochemical and immunofluorescence staining of brain tissue sections from harvested rat and mouse brains, and perform confocal microscopy.

 

Data Analysis

  • Bioinformatics. Analyze and interpret sc-RNA and single nuclei RNAseq, proteomics and gut microbiome data with appropriate statistical analysis, prepare data and figures and write manuscripts for publication in peer-reviewed journals.

  • Prepare manuscripts for publication.

  • Assist in preparing research proposals and progress reports.

 

Mentorship

  • Mentor undergraduate and graduate students in their research.

Why Texas A&M University?   

We are a prestigious university with strong traditions, Core Values, and a community of caring and collaboration. Amenities associated with a major university, such as sporting and cultural events, state-of-the-art recreation facilities, the Bush Library and Museum, and much more await you. Experience all that a big city has to offer but with a reasonable cost-of-living and no long commutes. 

 

Instructions to Applicants: Applications received by Texas A&M University must either have all job application data entered, or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to prepopulate the online application.  

All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution’s verification of credentials and/or other information required by the institution’s procedures, including the completion of the criminal history check.

Equal Opportunity/Veterans/Disability Employer.