Use Your Power for Purpose
You will have a profound impact on improving patients' lives by ensuring our evidence is scientifically robust and providing unbiased, medically essential expertise. Your role is vital in connecting sound scientific evidence with practical medical insights to enhance health and treatment outcomes. By bridging data gaps and empowering healthcare decisions regarding the safe and appropriate use of medicines, you will contribute significantly to patient care and treatment efficacy.
In addition to professional challenge, we offer a culture that supports and encourages ideas, and recognizes individual contribution.
ROLE SUMMARY:
Develops model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.
Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.
Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.
May help in providing support and/or development of quantitative methodology, pharmacometrics tools, software, hardware, and related business processes
ROLE RESPONSIBILITIES:
Responsible for the planning and execution of relevant quantitative analyses which may include population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure response, disease progression modeling, model-based meta-analysis, quantitative knowledge management, decision analysis, and MIDD strategy in collaboration with partners.
Prepares formal presentations and written reports to Pfizer standards.
Provide Quantitative Clinical Pharmacology expertise on multidisciplinary development teams, working closely with clinical pharmacologists, clinicians and statisticians to create clinical development plans that include assessments of a drug's efficacy, safety, and commercial viability.
May contributes with project teams/partners to regulatory documents.
Stays abreast of literature, government guidelines, and internal guidance as relates to pharmacometrics and MIDD, including internal SOPs and regulations in order to be a team resource of pharmacometric knowledge and applications.
Contribute to the development or improvement of our tools, processes and methodology, including involvement in internal cross-functional workgroups or initiatives, external alliances or committees, consortia and academic relationships.
BASIC QUALIFICATIONS:
PhD or equivalent degree with 0-3 years of relevant experience. Strong quantitative skills (e.g., pharmacometrics, pharmacokinetics, mechanistic modeling/systems pharmacology, literature meta-analyses, clinical trial simulations, statistics) are required.
Good understanding of Pharmacokinetics, Pharmacodynamics and Statistical Principles
Expertise in analysis and programming software (e.g., Nonmem, R).
Experience in pharmacometric analyses
Drug development and/or regulatory experience
We encourage applicants from different disciplines including clinical pharmacology, engineering, biostatistics, medicine, biology, etc.
Good communication skills (written, oral presentation).
PREFERRED QUALIFICATIONS:
Experience using NONMEM, R and/or PsN software is preferred.
Publications in relevant discipline
PHYSICAL/MENTAL REQUIREMENTS:
Ability to perform mathematic calculations and data analysis.
ADDITIONAL JOB DETAILS:
Last date to apply is December 18, 2025
Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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