Remix therapeutics

Head of Finance

Watertown, MA Full Time

Remix launched with a vision to transform patient’s lives through modulation of RNA processing. Our breakthrough science provides a path to identify small molecules that impact the expression of disease driving mRNAs and proteins. We take on the challenge of addressing drug targets in diseases of high unmet medical need to bring new therapeutic options to patients. Remix has a commitment to demonstrate the highest levels of scientific integrity with urgency because those patients are counting on us to deliver. With an in-house technology platform built from scratch, we have rapidly generated multiple drug discovery programs that are advancing towards the clinic.

Position Summary:

The Head of Finance will serve as the company’s senior finance leader, responsible for overseeing all aspects of accounting, financial operations, and compliance while contributing meaningfully to corporate strategy and long-term planning.

We are seeking a hands-on, highly experienced finance leader who has worked in a private biotech company with both pre-clinical and clinical programs. The ideal candidate will have strong technical accounting expertise, proven experience as a controller, and a demonstrated ability to manage both internal staff and external vendors. This individual must be comfortable working independently in a resource-constrained environment while also providing strategic financial guidance to the executive team.

Key Responsibilities:

Financial Operations & Compliance

  • Serve as the company’s controller, overseeing all accounting operations, financial reporting, and internal controls.
  • Ensure compliance with GAAP and all applicable regulations.
  • Manage monthly, quarterly, and annual close processes, as well as audit, tax, and regulatory filings.

Strategic Financial Leadership

  • Partner with the CBO/COO and leadership team to develop and refine the company’s financial strategy and long-term operating plan.
  • Provide scenario modeling, budget forecasts, and capital allocation recommendations.
  • Support fundraising activities, investor relations, and board-level financial reporting.

Operational Excellence

  • Implement and maintain scalable accounting and financial systems, processes, and tools.
  • Oversee cash flow management, including tracking of R&D expenses, clinical trial budgets, and operational spend.

Team & Vendor Management

  • Manage and mentor a small internal finance team, fostering growth and accountability.
  • Oversee and coordinate work of external vendors, including auditors, accounting consultants, tax advisors, and payroll providers.
  • Ensure vendors meet performance expectations, budgets, and timelines.

Qualifications:

Required

  • 10+ years of progressive finance and accounting experience, including senior leadership roles.
  • Proven track record in a private life sciences/biotech company with both clinical and pre-clinical programs.
  • Strong understanding of GAAP and biotech-specific accounting issues, including R&D accruals and clinical trial accounting.
  • Experience managing direct reports and external vendors.
  • Demonstrated ability to work independently in a fast-paced, entrepreneurial environment.

Preferred

  • CPA or MBA strongly preferred.
  • Experience supporting fundraising activities (venture capital, crossover, IPO readiness).
  • Familiarity with cost modeling for clinical development and pre-clinical programs.

Salary Range

$286,020 - $349,580 USD

This range reflects the expected base salary for this position, plus bonus, equity, and benefits as applicable.  Actual salaries may vary based on factors, such as skill, experience, and qualification for the role.